About: Structural and functional analysis of the S proteins of two human coronavirus OC43 strains adapted to growth in different cells

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About: Structural and functional analysis of the S proteins of two human coronavirus OC43 strains adapted to growth in different cells Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Structural and functional analysis of the S proteins of two human coronavirus OC43 strains adapted to growth in different cells
Creator	Herder, G Kiinkel, F
Source	Medline; PMC
abstract	The receptor-binding activity of strain CU (grown in MDCK I cells) and of strain VA (adapted to Vero cells) of human coronavirus OC43 was analyzed and compared with the binding activity of bovine coronavirus (BCV) and of the OC43 strain provided by the American Type Culture Collection (AT). Results obtained with resialylated erythrocytes indicated that the ability of the viruses to recognize 9-O-acetylated sialic acid in an α2,6-linkage decreased in the following order: AT>CU>BCV>VA. Only minor differences were observed with respect to the α2,3-linkage. The amino acid sequence of the S protein of strain CU and VA was derived from the nucleotide sequence of the cloned gene. Strain VA differed from strain CU in 34 positions, 18 in the S1 and 16 in the S2 subunit.
has issue date	1996-01-01(xsd:dateTime)
bibo:doi	10.1007/bf01718615
bibo:pmid	8712929
has license	no-cc
sha1sum (hex)	106b769328f09f2f27eb26ecfe9d11f60c8325e2
schema:url	https://doi.org/10.1007/bf01718615
resource representing a document's title	Structural and functional analysis of the S proteins of two human coronavirus OC43 strains adapted to growth in different cells
has PubMed Central identifier	PMC7086633
has PubMed identifier	8712929
schema:publication	Arch Virol
resource representing a document's body	covid:106b769328f09f2f27eb26ecfe9d11f60c8325e2#body_text
is schema:about of	named entity 'BCV' named entity 'Results' named entity 'positions' named entity 'proteins' named entity 'COMPARED' named entity 'PROVIDED' named entity 'BCV' named entity 'HUMAN CORONAVIRUS OC43' named entity '2C6' named entity 'OBTAINED' named entity 'DECREASED' named entity 'ANALYZED' named entity 'ABILITY' named entity 'MDCK' named entity 'SUBUNIT' named entity 'AMINO ACID SEQUENCE' named entity 'OC43' named entity 'CELLS' named entity 'VIRUSES' named entity 'STRAINS' named entity 'ORDER' named entity 'STRAIN' named entity 'FUNCTIONAL ANALYSIS' named entity 'HUMAN CORONAVIRUS' named entity 'S PROTEIN' named entity 'CLONED GENE' named entity 'BRIEF' named entity 'CELLS' named entity 'DIFFERENT' named entity 'STRUCTURAL' named entity 'ADAPTED' named entity 'BOVINE CORONAVIRUS' named entity 'MINOR' named entity 'VERO CELLS' named entity 'AMERICAN TYPE CULTURE COLLECTION' named entity 'INDICATED' named entity 'POSITIONS' named entity 'RECEPTOR' named entity 'NUCLEOTIDE SEQUENCE' named entity 'DERIVED' named entity 'PROTEIN ' named entity 'OBSERVED' named entity 'ERYTHROCYTES' named entity 'RESULTS' named entity 'BINDING ACTIVITY' named entity 'RECOGNIZE' named entity 'FOLLOWING' named entity 'RESPECT' named entity 'PROTEINS' named entity 'REPORT' named entity 'GROWTH' named entity '242' named entity 'O-ACETYLATED SIALIC ACID' covid:arg/106b769328f09f2f27eb26ecfe9d11f60c8325e2 named entity 'order' named entity 'activity' named entity 'cells' named entity 'cloned' named entity 'American Type Culture Collection' named entity 'receptor' named entity 'human coronavirus OC43' named entity 'erythrocytes' named entity 'sialic acid' named entity 'bovine coronavirus' named entity 'respect' named entity 'DEPC' named entity 'amino acids' named entity 'pH 8' named entity 'protein' named entity 'NaAc' named entity 'HCV' named entity 'OC43' named entity '2.0' named entity 'OC43' named entity 'OC43' named entity 'fusion reaction' named entity 'Vero cells' named entity 'agglutinate' named entity 'dTTP' named entity 'receptor'

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