About: How Could This Happen?: Narrowing Down the Contagion of COVID-19 and Preventing Acute Respiratory Distress Syndrome (ARDS)

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About: How Could This Happen?: Narrowing Down the Contagion of COVID-19 and Preventing Acute Respiratory Distress Syndrome (ARDS) Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	How Could This Happen?: Narrowing Down the Contagion of COVID-19 and Preventing Acute Respiratory Distress Syndrome (ARDS)
Creator	Allaerts, Wilfried
source	Medline; PMC
abstract	In this rapid commentary, a mini-review is given of the present state-of-knowledge regarding the etiology and epidemiology of the new coronavirus 2019-nCoV and the risks for developing Acute respiratory distress syndrome (ARDS). The available knowledge on the viral genomics, molecular biology and pathogenicity of viruses of the Coronaviridae family and other Nidovirales, forms a helpful template for understanding the present pandemic outbreak. However, important questions remain unanswered about the underlying mechanism causing the very high case fatality ratios (CFR) and mechanisms regarding severe reactions like ARDS, fatal cardiac and renal failures, associated with a number of important comorbidity factors. Immunological reactions to lung alveoles in particular (involving lung macrophages and alveolar epithelial cell damage) in late phase ARDS in SARS-like CoV diseases, so far may not have received enough attention. Finally a shortlist of questions for high priority further research is suggested.
has issue date	2020-04-25(xsd:dateTime)
bibo:doi	10.1007/s10441-020-09382-z
bibo:pmid	32335749
has license	no-cc
sha1sum (hex)	10c92caaafb3a84a577a96576ce04ca276773c25
schema:url	https://doi.org/10.1007/s10441-020-09382-z
resource representing a document's title	How Could This Happen?: Narrowing Down the Contagion of COVID-19 and Preventing Acute Respiratory Distress Syndrome (ARDS)
has PubMed Central identifier	PMC7183256
has PubMed identifier	32335749
schema:publication	Acta Biotheor
resource representing a document's body	covid:10c92caaafb3a84a577a96576ce04ca276773c25#body_text
is schema:about of	named entity 'viral' named entity 'coronavirus' named entity 'family' named entity 'reactions' named entity 'lung' »more»

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