About: Diagnosis of SARS-CoV-2 in children: accuracy of nasopharyngeal swab compared to nasopharyngeal aspirate.

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About: Diagnosis of SARS-CoV-2 in children: accuracy of nasopharyngeal swab compared to nasopharyngeal aspirate. Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Diagnosis of SARS-CoV-2 in children: accuracy of nasopharyngeal swab compared to nasopharyngeal aspirate.
Creator	Lunghi, Giovanna Gori, Andrea Marano, Giuseppe Bosis, Samantha Marchisio, Paola Castaldi, Silvana Giada, Maria Pietro, Biganzoli, Elia Boracchi, Patrizia Ceriotti, Ferruccio Luconi, Ester Pinzani, Raffaella Agostoni, Carlo Bertolozzi, Giuseppe Capecchi, Ester Cantoni, Barbara
Source	MedRxiv
abstract	The tests currently used for the direct identification of SARS-CoV-2 include specimens taken from upper and lower respiratory tract; recommendations from Word Health Organization prioritise nasopharyngeal swab (NS). In literature there are not available paediatric studies about the identification of SARS-CoV-2 through nasopharyngeal aspirate (NPA), but the use of NPA is deemed to be better than NS to identify respiratory viruses in children. The aim of our study is to evaluate diagnostic performances of NS compared to NPA for the detection of SARS-CoV-2 in children. We collected 300 paired samples (NS and NPA) from children hospitalized and followed up in our paediatric unit. We calculated the sensitivity and specificity of NS referred to NPA of the whole sample and then, considering both the age ([≥] and < 6 years old) and the period of collection (March vs follow up) as covariates in different analysis. The NS has a low sensitivity in detecting SARS-CoV-2 in children when referred to NPA; whereas its specificity results high. In children under 6 years of age, our results suggest to prefer the collection of NS, whenever possible. Though statistically not significant, the sensitivity of NS becomes higher if it is performed before NPA.
has issue date	2020-08-25(xsd:dateTime)
bibo:doi	10.1101/2020.08.20.20178012
has license	medrxiv
sha1sum (hex)	119f870c6884faf6201dcf1174459d51b4049003
schema:url	https://doi.org/10.1101/2020.08.20.20178012
resource representing a document's title	Diagnosis of SARS-CoV-2 in children: accuracy of nasopharyngeal swab compared to nasopharyngeal aspirate.
resource representing a document's body	covid:119f870c6884faf6201dcf1174459d51b4049003#body_text
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