About: Human coronavirus reinfection dynamics: lessons for SARS-CoV-2

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Human coronavirus reinfection dynamics: lessons for SARS-CoV-2
Creator	Deijs, Martin Rueda, Paloma Sastre, Patricia Jebbink, Maarten Bakker, Margreet Edridge, Arthur Kinsella, Cormac Van Der Hoek, Lia Hoste, Alexis Kaczorowska, Joanna Klein, Michelle Matser, Amy Prins, Maria
Source	MedRxiv
abstract	In the current SARS-CoV-2 pandemic a key unsolved question is the quality and duration of acquired immunity in recovered individuals. This is crucial to solve, however SARS-CoV-2 has circulated for under five months, precluding a direct study. We therefore monitored 10 subjects over a time span of 35 years (1985-2020), providing a total of 2473 follow up person-months, and determined a) their antibody levels following infection by any of the four seasonal human coronaviruses, and b) the time period after which reinfections by the same virus can occur. An alarmingly short duration of protective immunity to coronaviruses was found by both analyses. We saw frequent reinfections at 12 months post-infection and a substantial reduction in antibody levels as soon as 6 months post-infection.
has issue date	2020-05-18(xsd:dateTime)
bibo:doi	10.1101/2020.05.11.20086439
has license	medrxiv
sha1sum (hex)	1278a5d5da3fe03a98a85afd3424e82b84c018f0
schema:url	https://doi.org/10.1101/2020.05.11.20086439
resource representing a document's title	Human coronavirus reinfection dynamics: lessons for SARS-CoV-2
resource representing a document's body	covid:1278a5d5da3fe03a98a85afd3424e82b84c018f0#body_text
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