About: Pulmonary diseases induced by ambient ultrafine and engineered nanoparticles in twenty-first century

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About: Pulmonary diseases induced by ambient ultrafine and engineered nanoparticles in twenty-first century Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Pulmonary diseases induced by ambient ultrafine and engineered nanoparticles in twenty-first century
Creator	Xia, Tian Zhang, Zuo-Feng Liu, Sijin Mu, Lina Zhu, Yifang
Source	Medline; PMC
abstract	Air pollution is a severe threat to public health globally, affecting everyone in developed and developing countries alike. Among different air pollutants, particulate matter (PM), particularly combustion-produced fine PM (PM(2.5)) has been shown to play a major role in inducing various adverse health effects. Strong associations have been demonstrated by epidemiological and toxicological studies between increases in PM(2.5) concentrations and premature mortality, cardiopulmonary diseases, asthma and allergic sensitization, and lung cancer. The mechanisms of PM-induced toxicological effects are related to their size, chemical composition, lung clearance and retention, cellular oxidative stress responses and pro-inflammatory effects locally and systemically. Particles in the ultrafine range (<100 nm), although they have the highest number counts, surface area and organic chemical content, are often overlooked due to insufficient monitoring and risk assessment. Yet, ample studies have demonstrated that ambient ultrafine particles have higher toxic potential compared with PM(2.5). In addition, the rapid development of nanotechnology, bringing ever-increasing production of nanomaterials, has raised concerns about the potential human exposure and health impacts. All these add to the complexity of PM-induced health effects that largely remains to be determined, and mechanistic understanding on the toxicological effects of ambient ultrafine particles and nanomaterials will be the focus of studies in the near future.
has issue date	2016-10-08(xsd:dateTime)
bibo:doi	10.1093/nsr/nww064
bibo:pmid	28649460
has license	cc-by
sha1sum (hex)	13a1c758877b216e51c51e9ee532ab5c3e0c12fb
schema:url	https://doi.org/10.1093/nsr/nww064
resource representing a document's title	Pulmonary diseases induced by ambient ultrafine and engineered nanoparticles in twenty-first century
has PubMed Central identifier	PMC5473351
has PubMed identifier	28649460
schema:publication	Natl Sci Rev
resource representing a document's body	covid:13a1c758877b216e51c51e9ee532ab5c3e0c12fb#body_text
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