About: Identify the Risk Factors of COVID-19-Related Acute Kidney Injury: A Single-Center, Retrospective Cohort Study

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Identify the Risk Factors of COVID-19-Related Acute Kidney Injury: A Single-Center, Retrospective Cohort Study
Creator	Wang, Yuxi Li, Xing Wang, Jing Liu, Chang Wang, Xiaoning Li, Zhu Wang, Wang Feng, Chunxiang Hu, Jinqian Li, Haichao Liu, Shiliang Tharaux, Pierre-Louis Wang, Zhixian Zeng, Xiaoyong Yu, Kai Yuan, Xiaoning Zhu, Yunpeng Roumelioti, Maria-Eleni
Source	Medline; PMC
abstract	Background: The kidney is a target organ that could be infected by SARS-CoV-2, and acute kidney injury (AKI) was associated with a higher risk of COVID-19 patients' in-hospital death. However, no published works discussed about the risk factors of COVID-19 related AKI. Methods: We conducted a retrospective cohort study, recruiting COVID-19 inpatients from the Sino-French branch of Tongji Hospital. Demographic, clinical, treatment, and laboratory data were collected and compared. We used univariable and multivariable logistic regression methods to identify the risk factors of COVID-19-related AKI. Results: Of the 116 patients in our study, 12 (10.3%) were recognized as AKI, including 5 (4.3%) in-hospital AKI. Multivariable regression showed increasing odds of COVID-19-related AKI associated with COVID-19 clinical classification (OR = 8.155, 95% CI = 1.848–35.983, ref = non-critical, p = 0.06), procalcitonin more than 0.1 ng/mL (OR = 4.822, 95% CI = 1.095–21.228, p = 0.037), and estimated glomerular filtration rate (eGFR) <60 mL/min/1.73 m(2) (OR = 13.451, 95% CI = 1.617–111.891, p = 0.016). Conclusions: COVID-19-related AKI was likely to be related to multiorgan failure rather than the kidney tropism of SARS-CoV-2. The potential risk factors of COVID-19 clinical classification, procalcitonin more than 0.1 ng/mL, and eGFR <60 mL/min/1.73 m(2) could help clinicians to identify patients with kidney injury at an early stage.
has issue date	2020-07-28(xsd:dateTime)
bibo:doi	10.3389/fmed.2020.00436
bibo:pmid	32850917
has license	cc-by
sha1sum (hex)	14bd9f791c83121229bfb433c57edee8c645c56a
schema:url	https://doi.org/10.3389/fmed.2020.00436
resource representing a document's title	Identify the Risk Factors of COVID-19-Related Acute Kidney Injury: A Single-Center, Retrospective Cohort Study
has PubMed Central identifier	PMC7399623
has PubMed identifier	32850917
schema:publication	Front Med (Lausanne)
resource representing a document's body	covid:14bd9f791c83121229bfb433c57edee8c645c56a#body_text
is schema:about of	named entity 'IS A' covid:arg/14bd9f791c83121229bfb433c57edee8c645c56a named entity 'SARS-CoV-2' named entity 'acute kidney injury' named entity 'COVID' named entity 'COVID' named entity 'Acute Kidney Injury' named entity 'COVID-19' named entity 'Wuhan' named entity 'Coagulation disorder' named entity 'SARS-CoV-2' named entity 'SIRS' named entity 'eGFR' named entity 'respiratory failure' named entity 'AKI' named entity 'Austria' named entity 'AKI' named entity 'COVID-19' named entity 'LDH' named entity 'estimated glomerular filtration rate' named entity 'hypoxia' named entity 'China' named entity 'antiviral treatment' named entity 'COVID' named entity 'IL-2R' named entity 'CRRT' named entity 'overfitting' named entity 'logistic regression' named entity 'respiratory rate' named entity 'COVID' named entity 'systemic inflammatory response syndrome' named entity 'lymphocyte' named entity 'aspartate aminotransferase' named entity 'adenosine' named entity 'IBM Corporation' named entity 'AKI' named entity 'AKI' named entity 'cTnI' named entity 'TNFα' named entity 'COVID-19' named entity 'IL-10' named entity 'multiple-organ' named entity 'diagnostic criteria' named entity 'hs-CRP' named entity 'Wuhan' named entity 'categorical data' named entity 'diabetic nephropathy' named entity 'TNF-α' named entity 'activated partial thromboplastin time' named entity 'meta-analysis study' named entity 'neutrophil' named entity 'IL-6' named entity 'COVID-19' named entity 'AST' named entity 'probability' named entity 'statistically significant' named entity 'IL-2R' named entity 'hydrolysis' named entity 'risk factors' named entity 'urinary organs' named entity 'adverse events' named entity 'alkaline phosphatase' named entity 'respiratory support' named entity 'IL-2R'

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