About: Influenza Vaccination and COVID19 Mortality in the USA

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About: Influenza Vaccination and COVID19 Mortality in the USA Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Influenza Vaccination and COVID19 Mortality in the USA
Creator	Colantuoni, Elizabeth Dinalankara, Wikum Luidy Imada, Eddie Marchionni, Luigi Omar, Mohamed Parmigiani, Giovanni Zanettini, Claudio
source	MedRxiv; Medline; PMC
abstract	COVID-19 mortality rate is higher in the elderly and in those with preexisting chronic medical conditions. The elderly also suffer from increased morbidity and mortality from seasonal influenza infection, and thus annual influenza vaccination is recommended for them. In this study, we explore a possible area-level association between influenza vaccination coverage in people aged 65 years and older and the number of deaths from COVID-19. To this end, we used COVID-19 data until June 10, 2020 together with population health data for the United States at the county level. We fit quasi-Poisson regression models using influenza vaccination coverage in the elderly population as the independent variable and the number of deaths from COVID-19 as the outcome variable. We adjusted for a wide array of potential confounding variables using both county-level generalized propensity scores for influenza vaccination rates, as well as direct adjustment. Our results suggest that influenza vaccination coverage in the elderly population is negatively associated with mortality from COVID-19. This finding is robust to using different analysis periods, different thresholds for inclusion of counties, and a variety of methodologies for confounding adjustment. In conclusion, our results suggest a potential protective effect of the influenza vaccine on COVID-19 mortality in the elderly population. The significant public health implications of this possibility point to an urgent need for studying the relationship between influenza vaccination and COVID-19 mortality at the individual level, to investigate both the epidemiology and any underlying biological mechanism.
has issue date	2020-06-26(xsd:dateTime)
bibo:doi	10.1101/2020.06.24.20129817
bibo:pmid	32607525
has license	cc-by-nc-nd
sha1sum (hex)	151213814d39e65d2d5f598709db1b4964722982
schema:url	https://doi.org/10.1101/2020.06.24.20129817
resource representing a document's title	Influenza Vaccination and COVID19 Mortality in the USA
has PubMed Central identifier	PMC7325191
has PubMed identifier	32607525
schema:publication	medRxiv
resource representing a document's body	covid:151213814d39e65d2d5f598709db1b4964722982#body_text
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