About: Preparation and physicochemical property of chicken yolk immunoglobulin (IgY) against porcine transmissible gastroenteritis virus (TGEV)

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About: Preparation and physicochemical property of chicken yolk immunoglobulin (IgY) against porcine transmissible gastroenteritis virus (TGEV) Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Preparation and physicochemical property of chicken yolk immunoglobulin (IgY) against porcine transmissible gastroenteritis virus (TGEV)
Creator	Fan, Jinghui Li, Tanqing Zhang, Xiaobo Zuo, Yuzhu
Source	PMC
abstract	Oral administration of immunoglobulin prepared from the egg yolk of hens immunized with porcine transmissible gastroenteritis virus (TGEV) has been demonstrated to reduce piglets mortality significantly in our previous studies. In the present study, we investigated the stability of chicken yolk immunoglobulin (IgY) specific to TGEV by measuring the remaining activity by ELISA. The results showed that the IgY was stable between pH 4 and pH 11. In the incubation with pepsin at pH 4 and pH 6, about 90% and 100% of the IgY activity remained, respectively. IgY activity could remain approximately 80% at 60°C for 30 min, suggesting that pasteurization can be applied to sterilizing the product. The stability of IgY at 25°C and freezing-thawing treatment indicated that the IgY was easy to be conserved. These results highlight the attractive potential application of IgY as the antibodies of oral administration for treatment of TGEV infections.
has issue date	2009-06-15(xsd:dateTime)
bibo:doi	10.1007/s11703-009-0054-6
has license	no-cc
sha1sum (hex)	16a25bec69939f0ecf7e6679b9b862fe52b2ddc3
schema:url	https://doi.org/10.1007/s11703-009-0054-6
resource representing a document's title	Preparation and physicochemical property of chicken yolk immunoglobulin (IgY) against porcine transmissible gastroenteritis virus (TGEV)
has PubMed Central identifier	PMC7089202
schema:publication	Front Agric China
resource representing a document's body	covid:16a25bec69939f0ecf7e6679b9b862fe52b2ddc3#body_text
is schema:about of	named entity 'piglets' named entity 'hens' named entity 'THESE' named entity '100%' named entity 'EGG YOLK' named entity '30 MIN' named entity 'ANTIBODIES' named entity 'APPLICATION' named entity 'HENS' covid:arg/16a25bec69939f0ecf7e6679b9b862fe52b2ddc3 named entity 'STABLE' named entity 'OUR' named entity 'MEASURING' named entity 'EASY' named entity 'ORAL ADMINISTRATION' named entity 'YOLK' named entity 'ACTIVITY' named entity 'INVESTIGATED' named entity 'APPROXIMATELY' named entity 'IMMUNOGLOBULIN' named entity 'ABOUT' named entity 'PREVIOUS' named entity 'TO REDUCE' named entity 'PHYSICOCHEMICAL PROPERTY' named entity 'PORCINE TRANSMISSIBLE GASTROENTERITIS VIRUS' named entity 'CHICKEN' named entity 'REMAINING' named entity 'STABILITY' named entity 'INCUBATION' named entity 'YOLK' named entity 'IMMUNOGLOBULIN' named entity 'INFECTIONS' named entity 'PORCINE TRANSMISSIBLE GASTROENTERITIS VIRUS' named entity 'TREATMENT' named entity 'STUDIES' named entity 'POTENTIAL' named entity 'ELISA' named entity 'PASTEURIZATION' named entity 'RESULTS' named entity 'SPECIFIC' named entity 'PRESENT' named entity '90%' named entity 'PEPSIN' named entity 'ATTRACTIVE' named entity 'CONSERVED' named entity 'MORTALITY' named entity 'CHICKEN' named entity 'DEMONSTRATED' named entity 'IMMUNIZED' named entity 'TREATMENT INDICATED' named entity 'PREPARED' named entity 'STUDY' named entity 'IGY' named entity '80%' named entity 'PREPARATION' named entity 'PRODUCT' named entity 'APPLIED' named entity '60%' named entity 'FREEZING' named entity 'THAWING' named entity 'stability' named entity 'immunoglobulin' named entity 'easy' named entity 'demonstrated' named entity 'immunoglobulin' named entity 'chicken' named entity 'freezing-thawing' named entity 'activity' named entity 'TGEV' named entity 'antibodies' named entity 'yolk' named entity 'IgY' named entity 'pepsin' named entity 'IgY' named entity 'chicken' named entity 'yolk' named entity 'IgY' named entity 'IgY' named entity 'Oral administration' named entity 'pepsin'

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