About: Neurologic alterations in an HIV adult patient with pertussis: a case report

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Neurologic alterations in an HIV adult patient with pertussis: a case report
Creator	Trompa, Iván Arango-Granados, María, Camila
source	Medline; PMC
abstract	BACKGROUND: Pertussis is a highly contagious disease of public health interest caused by the bacterium Bordetella pertussis. Although its incidence has decreased substantially after the introduction of a vaccination, the burden of the disease remains high. Although the paroxysmal phase is highly disabling, complications are uncommon and more prevalent in children than in adults. The most frequent neurological complication is encephalopathy, but seizures, paresis, paraplegia, ataxias, aphasias, and decerebration postures have also been described. The complication of decerebration postures has not been previously reported in adults. CASE PRESENTATION: We present a video case of an adult HIV patient with severe coughing paroxysms, post-tussive emesis and syncope, whose workup confirmed the diagnosis of a B. pertussis respiratory infection. During hospitalization, he had fluctuant encephalopathy and post-tussive decerebration postures following paroxysms. He was treated with antibiotic therapy and finally sent home without residual neurological deficits. CONCLUSION: This case illustrates the biological plausibility of neurologic complications of pertussis in adults, which, albeit rare, can cause important morbidities. Future research should explore whether there are differences in the clinical presentation, risk factors and pathophysiology of the disease among adults or interventions aimed at preventing or treating pertussis encephalopathy.
has issue date	2020-07-02(xsd:dateTime)
bibo:doi	10.1186/s12879-020-05198-x
bibo:pmid	32615931
has license	cc-by
sha1sum (hex)	18445ebaae893ae8b97824b8ccfca6a2eb83602e
schema:url	https://doi.org/10.1186/s12879-020-05198-x
resource representing a document's title	Neurologic alterations in an HIV adult patient with pertussis: a case report
has PubMed Central identifier	PMC7330534
has PubMed identifier	32615931
schema:publication	BMC Infect Dis
resource representing a document's body	covid:18445ebaae893ae8b97824b8ccfca6a2eb83602e#body_text
is schema:about of	named entity 'postures' named entity 'diagnosis' covid:arg/18445ebaae893ae8b97824b8ccfca6a2eb83602e named entity 'presentation' named entity 'Conclusion' »more»

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