About: Can steroids reverse the severe COVID‐19 induced ‘cytokine storm’?

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Can steroids reverse the severe COVID‐19 induced ‘cytokine storm’? Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Can steroids reverse the severe COVID‐19 induced ‘cytokine storm’?
Creator	Gaga, Mina Giannakaki, Styliani Kolilekas, Lykourgos Levounets, Anastasia Loverdos, Konstantinos Vlassi, Lamprini Zervas, Eleftherios
source	Medline; PMC
abstract	Severe COVID‐19 is characterized by an excessive pro‐inflammatory cytokine storm, resulting in acute lung injury and development of ARDS. The role of corticosteroids is controversial in severe COVID‐19 pneumonia and associated hyper‐inflammatory syndrome. We reported a case series of six consecutive COVID‐19 patients with severe pneumonia, ARDS and laboratory indices of hyper‐inflammatory syndrome. All patients were treated early with a short course of corticosteroids, and clinical outcomes were compared before and after corticosteroids administration. All patients evaded intubation and intensive care admission, ARDS resolved within 11.8 days (median), viral clearance was achieved in 4 patients within 17.2 days (median), and all patients were discharged from the hospital in 16.8 days (median). Early administration of short course corticosteroids improves clinical outcome of patients with severe COVID‐19 pneumonia and evidence of immune hyper‐reactivity. This article is protected by copyright. All rights reserved.
has issue date	2020-06-12(xsd:dateTime)
bibo:doi	10.1002/jmv.26165
bibo:pmid	32530507
has license	no-cc
sha1sum (hex)	19237c6ab705024f4805225c4b91a048e4e958fc
schema:url	https://doi.org/10.1002/jmv.26165
resource representing a document's title	Can steroids reverse the severe COVID‐19 induced ‘cytokine storm’?
has PubMed Central identifier	PMC7307112
has PubMed identifier	32530507
schema:publication	J Med Virol
resource representing a document's body	covid:19237c6ab705024f4805225c4b91a048e4e958fc#body_text
is schema:about of	named entity 'patients' named entity 'patients' named entity 'discharged' named entity 'COVID-19' named entity 'laboratory' named entity 'development' named entity 'corticosteroids' named entity 'intensive care' named entity 'COVID-19' named entity 'case series' named entity 'patients' named entity 'pro-inflammatory cytokine' named entity 'ARDS' named entity 'COVID' named entity 'acute lung injury' named entity 'pneumonia' named entity 'COVID-19' named entity 'corticosteroids' named entity 'corticosteroids' named entity 'excessive' named entity 'COVID' named entity 'Greece' named entity 'symptom' named entity 'hypoxemia' named entity 'clinical phenotype' named entity 'ICU' named entity 'COVID' named entity 'prophylaxis' named entity 'diagnostic criteria' named entity 'smokers' named entity 'immune response' named entity 'viral shedding' named entity 'procalcitonin' named entity 'chemokines' named entity 'mmHg' named entity 'COVID' named entity 'nasopharyngeal swab' named entity 'oxygen therapy' named entity 'low-molecular-weight heparin' named entity 'dyspnea' named entity 'procalcitonin' named entity 'research ethics committee' named entity 'polymerase-chain-reaction' named entity 'IL-6' named entity 'ARDS' named entity 'lymphocyte' named entity 'hydroxychloroquine' named entity 'respiratory failure' named entity 'CRP' named entity 'interleukin 6' named entity 'adverse effects' named entity 'CRP' named entity 'fever' named entity 'CRP' named entity 'inflammatory' named entity 'influenza' named entity 'beta-lactam' named entity 'intubation' named entity 'ICU' named entity 'acute lung injury' named entity 'ICU' named entity 'cohort study' named entity 'pathogenetic' named entity 'sputum' named entity 'ferritin' named entity 'lung infection' named entity 'medical history' named entity 'septic shock' named entity 'hydroxychloroquine' named entity 'intubation' named entity 'COVID-19' named entity 'oseltamivir' named entity 'transaminitis' named entity 'diagnostic criteria' named entity 'cytokines'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2025 OpenLink Software