About: Clinical features in 52 patients with COVID-19 who have increased leukocyte count: a retrospective analysis

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Clinical features in 52 patients with COVID-19 who have increased leukocyte count: a retrospective analysis
Creator	Wang, Tao Zheng, Zhishui Zhao, Yang Li, Ruiyun Zeng, Shaolin Wu, Xiaojun Ding, Xuhong Nie, Hanxiang Zhao, Kaochang
source	Medline; PMC
abstract	Recent reports have showed that a proportion of patients with Coronavirus Disease 2019 (COVID-19) presented elevated leukocyte count. Clinical data about these patients is scarce. We aimed to evaluate the clinical findings of patients with COVID-19 who have increased leukocyte at admission. We retrospectively collected the clinical data on the 52 patients who have increased leukocyte count at admission from the 619 patients with confirmed COVID-19 who had pneumonia with abnormal features on chest CT scan in Renmin Hospital of Wuhan University in Wuhan, China, from February 3 to March 3, 2020. The mean age of the 52 patients with increased leukocyte count was 64.7 (SD 11.4) years, 32 (61.5%) were men and 47 (90.4%) had fever. Compared with the patients with non-increased leukocyte count, the patients with increased leukocyte count were significantly older (P < 0.01), were more likely to have underlying chronic diseases (P < 0.01), more likely to develop critically illness (P < 0.01), more likely to admit to an ICU (P < 0.01), more likely to receive mechanical ventilation (P < 0.01), had higher rate of death (P < 0.01) and the blood levels of neutrophil count and the serum concentrations of CRP and IL-6 were significantly increased, (P < 0.01). The older patients with COVID-19 who had underlying chronic disorders are more likely to develop leukocytosis. These patients are more likely to develop critical illness, with a high admission to an ICU and a high mortality rate.
has issue date	2020-07-10(xsd:dateTime)
bibo:doi	10.1007/s10096-020-03976-8
bibo:pmid	32651736
has license	no-cc
sha1sum (hex)	198d445fe13f1882d2dcc5bfb0a6c82b32df6e87
schema:url	https://doi.org/10.1007/s10096-020-03976-8
resource representing a document's title	Clinical features in 52 patients with COVID-19 who have increased leukocyte count: a retrospective analysis
has PubMed Central identifier	PMC7351641
has PubMed identifier	32651736
schema:publication	Eur J Clin Microbiol Infect Dis
resource representing a document's body	covid:198d445fe13f1882d2dcc5bfb0a6c82b32df6e87#body_text
is schema:about of	named entity 'Coronavirus' named entity 'levels' named entity 'chest' named entity 'collected' named entity 'patients' named entity 'disorders' named entity 'leukocyte' named entity 'COVID-19' named entity 'HIGHER' named entity 'CHEST CT SCAN' named entity 'COMPARED' named entity 'FEATURES' named entity 'NON-' named entity 'THESE' named entity 'LIKELY' named entity 'ADMIT' named entity 'FEVER' named entity 'critical illness' named entity 'mechanical ventilation' named entity 'elevated' named entity 'ICU' named entity 'blood' named entity 'high' named entity 'concentrations' named entity 'Disease' named entity 'evaluate' named entity 'patients' named entity 'CRP' named entity 'men' named entity 'leukocyte count' named entity 'pneumonia' named entity 'rate of death' named entity 'COVID' named entity 'neutrophil' named entity '0.01' named entity 'older patients' named entity 'COVID' named entity 'chronic diseases' named entity 'IL-6' named entity 'chronic disorders' named entity 'leukocyte count' named entity 'clinical findings' named entity 'ICU' named entity 'Clinical features' named entity 'COVID' named entity 'antibiotic therapy' named entity 'ICU' named entity 'demographic data' named entity 'leukocyte count' named entity 'COVID' named entity 'PCO2' named entity 'Demographic data' named entity 'COVID' named entity 'peripheral blood' named entity 'diagnostic criteria' named entity 'clinical practice' named entity 'arterial partial pressure of oxygen' named entity 'leukocyte count' named entity 'aspirates' named entity 'H3N2' named entity 'leukocyte count' named entity 'clinical outcomes' named entity 'Critically ill patients' named entity 'glucocorticoids' named entity 'Th17' named entity 'drug treatment' named entity 'systemic inflammation' named entity 'chronic diseases' named entity 'leukocytosis' named entity 'COVID' named entity 'chest CT scan' named entity 'serum concentrations' named entity 'COVID'

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