About: Self-powered portable melt electrospinning for in situ wound dressing

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About: Self-powered portable melt electrospinning for in situ wound dressing Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Self-powered portable melt electrospinning for in situ wound dressing
Creator	Zhang, Jun Gao, Yuan Liu, Jiang-Jun Liu, Xiao-Fei Long, Yun-Ze Wang, Xiao-Xiong Xiang, Hong-Fei Zhao, Ying-Tao
Source	PMC
abstract	BACKGROUND: Electrospun (e-spun) nanofibers for wound dressing have attracted wide attention due to its large specific surface area, large porosity and breathability. Compared with solution electrospinning (e-spinning), melt e-spinning is more bio-friendly without toxic solvent participation, which provides the possibility of in situ e-spinning on wounds directly. However, previously reported melt e-spinning devices were usually bulky and cumbersome due to their necessary heating unit, and different components were separated to avoid electrostatic interference. RESULTS: In this article, we report on a self-powered hand-held melt e-spinning gun which can work without any external power supply (outdoors). The problem of electrostatic interference for this integrated device was solved by using a special high heat transfer insulation unit. The apparatus is easy and safe to operate by a single hand due to its small volume (24 × 6 × 13 cm(3)) and light weight (about 450 g). Some biodegradable polymers, for example, polycaprolactone (PCL) fibers were successful e-spun onto wounds directly by using this dressing gun. CONCLUSIONS: PCL fibrous membrane has good biocompatibility and can be in situ electrospun to wound surface as a wound dressing by the portable melt e-spinning gun. Besides wound dressing, this hand-held melt e-spinning gun may be used in 3D printing and experimental teaching demonstration aids.
has issue date	2020-08-10(xsd:dateTime)
bibo:doi	10.1186/s12951-020-00671-w
has license	cc-by
sha1sum (hex)	1aa2c31c6e5f358cf3ddc3977d6c2f81cf07f24b
schema:url	https://doi.org/10.1186/s12951-020-00671-w
resource representing a document's title	Self-powered portable melt electrospinning for in situ wound dressing
has PubMed Central identifier	PMC7416801
schema:publication	J Nanobiotechnology
resource representing a document's body	covid:1aa2c31c6e5f358cf3ddc3977d6c2f81cf07f24b#body_text
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