About: Clinical cystoisosporosis associated to porcine cytomegalovirus (PCMV, Suid herpesvirus 2) infection in fattening pigs

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About: Clinical cystoisosporosis associated to porcine cytomegalovirus (PCMV, Suid herpesvirus 2) infection in fattening pigs Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Clinical cystoisosporosis associated to porcine cytomegalovirus (PCMV, Suid herpesvirus 2) infection in fattening pigs
Creator	Basso, Walter Bürgi, Esther Hilbe, Monika Marti, Hanna Sidler, Xaver Stahel, Anina Sydler, Titus
Source	Elsevier; Medline; PMC
abstract	Cystoisospora (syn. Isospora) suis is the causative agent of neonatal porcine coccidiosis and one of the main causes of diarrhoea in suckling piglets worldwide. Infection with porcine cytomegalovirus (PCMV, Suid herpesvirus 2) causes inclusion body rhinitis in pigs. In a Swiss pig herd (n = 2 boars, 7 sows, 2 gilts, 18 finishing pigs, 30 fattening pigs, 54 suckling piglets), an outbreak of PCMV infection with high morbidity in all age categories, characterized by fever, anorexia, reduced general condition, respiratory signs and increased piglet mortality, was diagnosed by histopathology and molecular methods. Five fattening pigs (age ~ 17 weeks) additionally showed diarrhoea, not typical for PCMV infections, and one fattener had to be euthanized due to poor condition. Histopathologically, severe fibrinopurulent jejunoileitis with extensive atrophy and fusion of intestinal villi, loss of goblet cells and crypt abscesses associated to C. suis infection were present. In the liver, herpesvirus intranuclear inclusion bodies were observed and PCMV was confirmed by PCR/sequencing. No further infectious causes of diarrhoea (i.e. Rotavirus A; TGEV; PEDV; PCV-2; enterotoxigenic Escherichia coli or Lawsonia intracellularis) were detected in the euthanized fattener. Coproscopically, C. suis oocysts were identified in the faeces from further fatteners with diarrhoea. While C. suis usually produces disease only in suckling piglets, its association with severe intestinal lesions and diarrhoea in ~ 17-week-old fatteners was surprising. It is supposed that the underlying PCMV infection might have contributed to the presentation of clinical cystoisosporosis in fattening pigs. The interaction mechanisms between these two pathogens are unknown.
has issue date	2017-09-21(xsd:dateTime)
bibo:doi	10.1016/j.parint.2017.09.007
bibo:pmid	28942051
has license	no-cc
sha1sum (hex)	1ab371121f26f1468b469e5673ea055eeb8e62ae
schema:url	https://doi.org/10.1016/j.parint.2017.09.007
resource representing a document's title	Clinical cystoisosporosis associated to porcine cytomegalovirus (PCMV, Suid herpesvirus 2) infection in fattening pigs
has PubMed Central identifier	PMC7108397
has PubMed identifier	28942051
schema:publication	Parasitol Int
resource representing a document's body	covid:1ab371121f26f1468b469e5673ea055eeb8e62ae#body_text
is schema:about of	named entity 'SWISS' named entity 'INTERACTION' named entity 'LOSS OF' named entity 'INFECTIONS' named entity 'HIGH' named entity 'OLD' named entity 'WORLDWIDE' named entity 'CAUSATIVE AGENT' named entity 'LESIONS' named entity 'ONE OF' named entity 'WEEK' named entity 'PATHOGENS' named entity 'CLINICAL' named entity 'INTRANUCLEAR INCLUSION BODIES' named entity 'CONDITION' named entity 'AGE CATEGORIES' named entity 'LIVER' named entity 'RESPIRATORY' named entity 'FAECES' named entity 'PRESENTATION' named entity 'COCCIDIOSIS' named entity 'PIG' named entity 'TYPICAL' named entity 'SOWS' named entity 'INCLUSION BODY' named entity 'ENTEROTOXIGENIC ESCHERICHIA COLI' named entity 'CRYPT ABSCESSES' named entity 'PCR' named entity 'Rotavirus A' named entity 'signs' named entity 'PCV' named entity 'outbreak' named entity 'herpesvirus' named entity 'presentation' named entity 'ASSOCIATED' covid:arg/1ab371121f26f1468b469e5673ea055eeb8e62ae named entity 'CLINICAL' named entity 'HERPESVIRUS' named entity 'SIGNS' named entity 'DISEASE' named entity 'FUSION' named entity 'PCR' named entity 'FIBRINOPURULENT' named entity 'EUTHANIZED' named entity 'DUE TO' named entity 'MORBIDITY' named entity 'FATTENING' named entity 'MORTALITY' named entity 'PORCINE' named entity 'RHINITIS' named entity 'UNDERLYING' named entity 'GOBLET CELLS' named entity 'PIGS' named entity 'IDENTIFIED' named entity 'INCREASED' named entity 'HISTOPATHOLOGY' named entity 'SUID HERPESVIRUS 2' named entity 'INTESTINAL' named entity 'INFECTION' named entity 'PIGS' named entity 'FATTENING' named entity 'DIARRHOEA' named entity 'BOARS' named entity 'PRESENT' named entity 'INFECTIOUS' named entity 'ANOREXIA' named entity '28I' named entity 'MOLECULAR' named entity 'EXTENSIVE' named entity 'METHODS' named entity 'DIAGNOSED' named entity 'CAUSES' named entity 'ASSOCIATED' named entity 'OOCYSTS' named entity 'PCV'

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