About: Successful natural interferon-β plus ribavirin therapy in a chronic hepatitis C patient after discontinuation of interferon-α treatment due to arrhythmia and interstitial pneumonia

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About: Successful natural interferon-β plus ribavirin therapy in a chronic hepatitis C patient after discontinuation of interferon-α treatment due to arrhythmia and interstitial pneumonia Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Successful natural interferon-β plus ribavirin therapy in a chronic hepatitis C patient after discontinuation of interferon-α treatment due to arrhythmia and interstitial pneumonia
Creator	Adachi, Kayo Hayashi, Mikihito Ishii, Toshiya Kumano, Reiko Kumon, Daisuke Sato, Akira Yamada, Takayuki Yamauchi, Masahiro
source	Medline; PMC
abstract	A 71-year-old female patient with hepatitis C virus genotype 1 had previously discontinued interferon (IFN)-α plus ribavirin therapy, pegylated IFN-α (pegIFN-α) monotherapy, and natural IFN-α monotherapy because of arrhythmia, interstitial pneumonia, and severe neurovegetative symptoms. She subsequently completed 72 weeks of natural IFN-β plus ribavirin therapy without remarkable adverse effects and achieved a sustained viral response, suggesting differences in the pharmacological properties and biological effects of IFN-α and IFN-β. Thus, natural IFN-β plus ribavirin therapy may be a treatment option for patients with poor tolerance to IFN-α or pegIFN-α treatments.
has issue date	2014-06-06(xsd:dateTime)
bibo:doi	10.1007/s12328-014-0500-8
bibo:pmid	25132867
has license	no-cc
sha1sum (hex)	1b6616fe20c678e18915ea2b6fab8b22309b45b6
schema:url	https://doi.org/10.1007/s12328-014-0500-8
resource representing a document's title	Successful natural interferon-β plus ribavirin therapy in a chronic hepatitis C patient after discontinuation of interferon-α treatment due to arrhythmia and interstitial pneumonia
has PubMed Central identifier	PMC4124242
has PubMed identifier	25132867
schema:publication	Clin J Gastroenterol
resource representing a document's body	covid:1b6616fe20c678e18915ea2b6fab8b22309b45b6#body_text
is schema:about of	named entity 'NATURAL' named entity 'response' named entity 'natural' named entity 'pegylated' named entity 'INTERSTITIAL PNEUMONIA' named entity 'RIBAVIRIN' named entity 'PREVIOUSLY' named entity 'NATURAL' named entity 'POOR' named entity 'HEPATITIS C VIRUS GENOTYPE 1' named entity 'BIOLOGICAL' named entity 'PHARMACOLOGICAL' named entity 'TREATMENTS' named entity 'SYMPTOMS' named entity 'WEEKS' named entity 'INTERFERON ' named entity 'MONOTHERAPY' named entity 'EFFECTS' covid:arg/1b6616fe20c678e18915ea2b6fab8b22309b45b6 named entity 'CHRONIC HEPATITIS C' named entity 'DUE TO' named entity 'ADVERSE EFFECTS' named entity 'TREATMENT OPTION' named entity 'SEVERE' named entity 'INTERSTITIAL PNEUMONIA' named entity 'DISCONTINUATION' named entity 'INTERFERON-B' named entity 'THERAPY' named entity 'ARRHYTHMIA' named entity 'SUCCESSFUL' named entity 'INTERFERON' named entity 'TREATMENT' named entity 'PATIENT' named entity 'THERAPY' named entity 'SUSTAINED VIRAL RESPONSE' named entity 'IFN' named entity 'YEAR' named entity 'IFN-A' named entity 'DISCONTINUED' named entity 'RIBAVIRIN' named entity 'PEGYLATED' named entity 'ARRHYTHMIA' named entity 'PROPERTIES' named entity 'FEMALE PATIENT' named entity 'COMPLETED' named entity 'MAY BE A' named entity 'TOLERANCE' named entity 'PATIENTS' named entity 'OLD' named entity 'IFN-a' named entity 'ribavirin' named entity 'symptoms' named entity 'interstitial pneumonia' named entity 'sustained' named entity 'neurovegetative symptoms' named entity 'IFN-a' named entity 'hepatitis C virus genotype' named entity 'pharmacological properties' named entity 'ribavirin' named entity 'interferon' named entity 'interferon' named entity 'fatigue' named entity 'shortness of breath' named entity 'ECG' named entity 'anti-viral' named entity 'UDCA' named entity 'UDCA' named entity 'IFN' named entity 'type 2' named entity 'IFN' named entity 'adverse effects' named entity 'AFP' named entity 'genotype' named entity '7th week'

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