About: Geographical Accessibility to Glucose-6-Phosphate Dioxygenase Deficiency Point-of-Care Testing for Antenatal Care in Ghana

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About: Geographical Accessibility to Glucose-6-Phosphate Dioxygenase Deficiency Point-of-Care Testing for Antenatal Care in Ghana Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Geographical Accessibility to Glucose-6-Phosphate Dioxygenase Deficiency Point-of-Care Testing for Antenatal Care in Ghana
Creator	Mashamba-Thompson, Tivani Moshabela, Mosa Drain, Paul Adogboba, Duncan Adu, Kwame Bawontuo, Vitalis Kuupiel, Desmond
Source	Medline; PMC
abstract	Background: Glucose-6-Phosphate Dehydrogenase (G6PD) deficiency screening test is essential for malaria treatment, control, and elimination programs. G6PD deficient individuals are at high risk of severe hemolysis when given anti-malarial drugs such as primaquine, quinine, other sulphonamide-containing medicines, and chloroquine, which has recently been shown to be potent for the treatment of coronavirus disease (COVID-19). We evaluated the geographical accessibility to POC testing for G6PD deficiency in Ghana, a malaria-endemic country. Methods: We obtained the geographic information of 100 randomly sampled clinics previously included in a cross-sectional survey. We also obtained the geolocated data of all public hospitals providing G6PD deficiency testing services in the region. Using ArcGIS 10.5, we quantified geographical access to G6PD deficiency screening test and identified clinics as well as visualize locations with poor access for targeted improvement. The travel time was estimated using an assumed speed of 20 km per hour. Findings: Of the 100 clinics, 58% were Community-based Health Planning and Services facilities, and 42% were sub-district health centers. The majority (92%) were Ghana Health Service facilities, and the remaining 8% were Christian Health Association of Ghana facilities. Access to G6PD deficiency screening test was varied across the districts, and G6PD deficiency screening test was available in all eight public hospitals. This implies that the health facility-to-population ratio for G6PD deficiency testing service was approximately 1:159,210 (8/1,273,677) population. The spatial analysis quantified the current mean distance to a G6PD deficiency testing service from all locations in the region to be 34 ± 14 km, and travel time (68 ± 27 min). The estimated mean distance from a clinic to a district hospital for G6PD deficiency testing services was 15 ± 11 km, and travel time (46 ± 33 min). Conclusion: Access to POC testing for G6PD deficiency in Ghana was poor. Given the challenges associated with G6PD deficiency, it would be essential to improve access to G6PD deficiency POC testing to facilitate administration of sulphadoxine-pyrimethamine to pregnant women, full implementation of the malaria control program in Ghana, and treatment of COVID-19 patients with chloroquine in malaria-endemic countries. To enable the World Health Organization include appropriate G6PD POC diagnostic tests in its list of essential in-vitro diagnostics for use in resource-limited settings, we recommend a wider evaluation of available POC diagnostic tests for G6PD deficiency, particularly in malaria-endemic countries.
has issue date	2020-04-16(xsd:dateTime)
bibo:doi	10.3390/diagnostics10040229
bibo:pmid	32316233
has license	cc-by
sha1sum (hex)	1bbdefc1fa3b84cace7f457a886e4b98aeab68d7
schema:url	https://doi.org/10.3390/diagnostics10040229
resource representing a document's title	Geographical Accessibility to Glucose-6-Phosphate Dioxygenase Deficiency Point-of-Care Testing for Antenatal Care in Ghana
has PubMed Central identifier	PMC7235997
has PubMed identifier	32316233
schema:publication	Diagnostics (Basel)
resource representing a document's body	covid:1bbdefc1fa3b84cace7f457a886e4b98aeab68d7#body_text
is schema:about of	named entity 'randomly' named entity 'diagnostic tests' named entity 'testing' named entity 'screening test' named entity 'The' named entity 'ratio' named entity 'The majority' named entity 'distance' named entity 'distance' named entity 'travel' named entity 'G6PD deficiency' named entity 'geographic' named entity 'G6PD deficiency' named entity 'Ghana' named entity 'COUNTRY' named entity 'SERVICE' named entity 'GIVEN' named entity 'PROGRAMS' named entity 'ITS' named entity 'HEMOLYSIS ' named entity 'PROGRAM' named entity 'USING' named entity 'IDENTIFIED' named entity 'ACCESSIBILITY' named entity 'ANTENATAL CARE' named entity 'DIOXYGENASE' named entity 'min' named entity 'varied' named entity 'G6PD deficiency' named entity 'G6PD deficiency' named entity 'access' named entity 'full' named entity 'World Health Organization' named entity 'health' named entity 'testing' named entity 'locations' named entity 'implies' named entity 'Ghana' named entity 'quantified' named entity 'chloroquine' named entity 'cross-sectional survey' named entity 'G6PD' named entity 'G6PD deficiency' named entity 'spatial analysis' named entity 'diagnostic tests' named entity 'endemic' named entity 'G6PD deficiency' named entity 'in-vitro' named entity 'COVID-19' named entity 'pyrimethamine' named entity 'Glucose-6-Phosphate Dehydrogenase' named entity 'Ghana Health Service' named entity 'ArcGIS' named entity 'G6PD deficiency' named entity 'Dioxygenase' named entity 'Point-of-Care Testing' named entity 'Philippines' named entity 'G6PD deficiency' named entity 'Bangladesh' named entity 'G6PD deficiency' named entity 'University of Ghana' named entity 'endemic' named entity 'heterogeneity' named entity 'microscopy' named entity 'G6PD deficiency' named entity 'anemia' named entity 'follow-up' named entity 'G6PD deficiency' named entity 'Ghana' named entity 'malaria' named entity 'CHPS' named entity 'chloroquine' named entity 'G6PD deficiency' named entity 'G6PD deficiency' named entity 'Remote Sensing'

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