About: A telemetric study of physiologic changes in mice with induced autoimmune encephalomyelitis

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	A telemetric study of physiologic changes in mice with induced autoimmune encephalomyelitis
Creator	Jones, Richard Buenafe, Abigail Moes, Nicole Oken, Barry Zwickey, Heather
Source	Medline; PMC
abstract	Dysfunction of the autonomic nervous system may be an important component of disease progression in multiple sclerosis (MS), a paralytic inflammatory autoimmune disease of the central nervous system. Using the experimental autoimmune encephalomyelitis mouse model of MS, the authors carried out a pilot study to investigate whether telemetric monitoring might be a feasible approach for detecting disturbances in the autonomic control of heart rate and blood pressure after disease induction. Telemetric monitoring devices that were implanted in mice provided useful information regarding the physiologic changes that accompanied disease induction and progression. Changes were observed in heart rate, blood pressure, heart rate variability and diurnal rhythm immediately before and after disease onset. The device implantation procedure did not seem to alter the course of disease. Further investigation may establish these methods as a system for studying the relationships between MS progression and autonomic regulation of physiological status.
has issue date	2008-01-01(xsd:dateTime)
bibo:doi	10.1038/laban0808-361
bibo:pmid	18650824
has license	no-cc
sha1sum (hex)	1cad2afc611bc4918557dcbdd4682800abb6b2e3
schema:url	https://doi.org/10.1038/laban0808-361
resource representing a document's title	A telemetric study of physiologic changes in mice with induced autoimmune encephalomyelitis
has PubMed Central identifier	PMC7091732
has PubMed identifier	18650824
schema:publication	Lab Anim (NY)
resource representing a document's body	covid:1cad2afc611bc4918557dcbdd4682800abb6b2e3#body_text
is schema:about of	named entity 'telemetry' named entity 'parasympathetic' named entity 'carotid artery' named entity 'signs of disease' named entity 'telemetry' named entity 'telemetric' named entity 'disease pattern' named entity 'mice' named entity 'mice' named entity 'regulatory process' named entity 'HRV' named entity 'hormonal signals' named entity 'mice' named entity 'St. Paul, MN' named entity 'mice' named entity 'telemetric' named entity '5.0' named entity 'power spectrum' named entity 'Spectral analyses' named entity 'time domain' named entity 'immune response' named entity 'autonomic nervous' named entity 'innervation' named entity 'blood pressure' named entity 'remission' named entity 'autonomic dysfunction' named entity 'parvovirus' named entity 'Sendai virus' named entity '5.0' named entity 'EAE' named entity 'mice' named entity 'mice' named entity 'EAE' named entity 'fatigue' named entity 'mice' named entity 'murine' named entity 'nocturnal' named entity 'telemetry' named entity 'passive transfer' named entity 'mice' named entity 'EAE' named entity 'mice' named entity 'autonomic dysfunction' named entity 'paraplegia' named entity 'L-glutamine' named entity 'rotavirus' named entity 'mice' named entity 'mice' named entity 'lysed' named entity 'circadian rhythm' named entity 'pathogen' named entity 'dextrose' named entity 'immunization' named entity 'EAE' named entity 'power spectral density' named entity 'diurnal' named entity 'EAE' named entity 'EAE' named entity 'EAE' named entity 'parasites' named entity 'mice' named entity 'murine' named entity 'animal models' named entity 'L-glutamine' named entity 'red blood cells' named entity 'zeitgeber' named entity 'neurodegenerative disease' named entity 'radiofrequency' named entity 'parasympathetic' named entity 'light cycle' named entity 'Jackson Laboratory' named entity 'telemetry' named entity 'EAE' named entity 'midbrain' named entity 'reovirus' named entity 'mice' named entity 'Veterinary Medical'

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