About: A systematic review of MERS-CoV seroprevalence and RNA prevalence in dromedary camels: Implications for animal vaccination

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About: A systematic review of MERS-CoV seroprevalence and RNA prevalence in dromedary camels: Implications for animal vaccination Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	A systematic review of MERS-CoV seroprevalence and RNA prevalence in dromedary camels: Implications for animal vaccination
Creator	Jombart, Thibaut Ferguson, Neil Van Kerkhove, Maria Dighe, Amy
Source	Elsevier; Medline; PMC
abstract	Human infection with Middle East Respiratory Syndrome Coronavirus (MERS-CoV) is driven by recurring dromedary-to-human spill-over events, leading decision-makers to consider dromedary vaccination. Dromedary vaccine candidates in the development pipeline are showing hopeful results, but gaps in our understanding of the epidemiology of MERS-CoV in dromedaries must be addressed to design and evaluate potential vaccination strategies. We aim to bring together existing measures of MERS-CoV infection in dromedary camels to assess the distribution of infection, highlighting knowledge gaps and implications for animal vaccination. We systematically reviewed the published literature on MEDLINE, EMBASE and Web of Science that reported seroprevalence and/or prevalence of active MERS-CoV infection in dromedary camels from both cross-sectional and longitudinal studies. 60 studies met our eligibility criteria. Qualitative syntheses determined that MERS-CoV seroprevalence increased with age up to 80–100% in adult dromedaries supporting geographically widespread endemicity of MERS-CoV in dromedaries in both the Arabian Peninsula and countries exporting dromedaries from Africa. The high prevalence of active infection measured in juveniles and at sites where dromedary populations mix should guide further investigation – particularly of dromedary movement – and inform vaccination strategy design and evaluation through mathematical modelling.
has issue date	2019-12-01(xsd:dateTime)
bibo:doi	10.1016/j.epidem.2019.100350
bibo:pmid	31201040
has license	cc-by
sha1sum (hex)	1cc16427f0accab0051485dbbb73dbce1d0848e4
schema:url	https://doi.org/10.1016/j.epidem.2019.100350
resource representing a document's title	A systematic review of MERS-CoV seroprevalence and RNA prevalence in dromedary camels: Implications for animal vaccination
has PubMed Central identifier	PMC6899506
has PubMed identifier	31201040
schema:publication	Epidemics
resource representing a document's body	covid:1cc16427f0accab0051485dbbb73dbce1d0848e4#body_text
is schema:about of	named entity 'decision-makers' named entity 'vaccination' named entity 'leading' named entity 'Web' named entity 'Africa' named entity 'development' named entity 'longitudinal studies' named entity 'seroprevalence' named entity 'VACCINATION' named entity 'REVIEW OF' named entity 'INFECTION' named entity 'CAMELS' named entity 'MATHEMATICAL MODELLING' named entity 'CAMELS' named entity 'JUVENILES' named entity 'WHERE' named entity 'HOPEFUL' named entity 'MET' named entity 'RECURRING' named entity 'STUDIES' named entity 'CROSS-SECTIONAL' named entity 'GUIDE' named entity 'POPULATIONS' named entity 'DRIVEN' named entity 'MEASURES' named entity 'EVALUATION' named entity 'PIPELINE' named entity 'ACTIVE' named entity 'LITERATURE' named entity 'EPIDEMIOLOGY' named entity 'BUT' named entity 'EVENTS' named entity 'PUBLISHED' named entity 'SYNDROME' named entity 'HIGHLIGHTING' named entity 'COUNTRIES' named entity '100%' named entity 'MEASURED' named entity 'MEDLINE' named entity 'DECISION' named entity 'TO BRING TOGETHER' named entity 'DEVELOPMENT' named entity 'SPILL' named entity 'KNOWLEDGE' named entity 'REPORTED' named entity 'MAKERS' named entity 'SEROPREVALENCE' named entity 'INVESTIGATION' named entity 'UNDERSTANDING' named entity 'QUALITATIVE' named entity 'ANIMAL' named entity 'RESPIRATORY' named entity 'PREVALENCE' named entity 'DESIGN' named entity 'CORONAVIRUS' named entity 'STRATEGY' named entity 'INCREASED' named entity 'PREVALENCE' named entity 'MIX' named entity 'AGE' named entity 'SCIENCE' named entity 'WIDESPREAD' named entity 'MERS-COV' named entity 'ELIGIBILITY CRITERIA' named entity 'LEADING' named entity 'HUMAN' named entity 'HIGH PREVALENCE' named entity 'ADULT' named entity 'POTENTIAL' named entity 'RNA' named entity 'SYSTEMATIC REVIEW' named entity 'MIDDLE EAST' named entity 'DROMEDARY' named entity 'RESULTS' named entity 'VACCINATION' named entity 'EVALUATE' named entity 'ENDEMICITY' named entity 'DETERMINED'

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