About: Etiology of acute bronchiolitis and the relationship with meteorological conditions in hospitalized infants in China

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Etiology of acute bronchiolitis and the relationship with meteorological conditions in hospitalized infants in China
Creator	Xu, Jun Ji, Wei Chen, Zheng-Rong Shao, Xue-Jun Wang, Yu-Qing Yan, Yong-Dong Zhang, Xue-Lan
Source	Elsevier; Medline; PMC
abstract	BACKGROUND/PURPOSE: To investigate the prevalence of common viruses and Mycoplasma pneumoniae (MP) in hospitalized infants with acute bronchiolitis and study the relationship between bronchiolitis and meteorological conditions. METHODS: A 2-year prospective study was conducted on infants with a first episode of bronchiolitis admitted to Respiratory Department of Suzhou Children's Hospital. Demographic and clinical characteristics and meteorological conditions were obtained and analyzed. RESULTS: Pathogens were identified in 59.6% of 998 cases analyzed. The most frequent pathogen identified was respiratory syncytial virus (28.7%), followed by human bocavirus (11.6%), MP (9.0%), human parainfluenza virus-3 (7.8%), human metapneumovirus (6.6%), influenza A (3.5%), adenovirus (1.0%), and human parainfluenza virus-1 (0.3%). The clinical scores in children with MP or human metapneumovirus single infections, based on the assessment of severity of acute bronchiolitis, were significantly lower than in children with respiratory syncytial virus single infections. Respiratory syncytial virus had the strongest inverse correlation with mean temperature, followed by influenza A and human metapneumovirus. In addition, MP and human parainfluenza virus-3 showed positive correlations with mean temperature. CONCLUSION: Although respiratory syncytial virus was the most frequent pathogen in patients in whom bronchiolitis was diagnosed, other pathogens, including newly identified viruses and MP, also play important roles in infants with bronchiolitis. Different respiratory pathogens have different traits in response to certain meteorological conditions.
has issue date	2013-02-08(xsd:dateTime)
bibo:doi	10.1016/j.jfma.2012.12.013
bibo:pmid	24961189
has license	no-cc
sha1sum (hex)	1cd18202a1ae525d8bf2feecfe790f34c16fe1d6
schema:url	https://doi.org/10.1016/j.jfma.2012.12.013
resource representing a document's title	Etiology of acute bronchiolitis and the relationship with meteorological conditions in hospitalized infants in China
has PubMed Central identifier	PMC7173297
has PubMed identifier	24961189
schema:publication	J Formos Med Assoc
resource representing a document's body	covid:1cd18202a1ae525d8bf2feecfe790f34c16fe1d6#body_text
is schema:about of	named entity 'infections' named entity 'hospitalized' named entity 'parainfluenza virus' named entity 'frequent' named entity 'bronchiolitis' named entity 'frequent' named entity 'infants' named entity 'Mycoplasma pneumoniae' named entity 'meteorological' named entity 'bronchiolitis' named entity 'respiratory syncytial virus' named entity 'infants' named entity 'correlations' named entity 'influenza A' named entity 'Respiratory syncytial virus' named entity 'influenza A' named entity 'meteorological' named entity 'positive' named entity 'adenovirus' named entity 'bronchiolitis' named entity 'bronchiolitis' named entity 'acute bronchiolitis' named entity 'respiratory syncytial virus' named entity 'viruses' named entity 'human metapneumovirus' named entity 'human parainfluenza virus' named entity 'Etiology' named entity 'China' named entity 'primers' named entity 'Suzhou' named entity 'emerging viruses' named entity 'Promega' named entity 'lower respiratory tract infection' named entity 'nasopharyngeal' named entity 'real-time PCR' named entity 'RSV' named entity 'respiratory infections' named entity 'PCR' named entity 'pathogen' named entity 'tetramethyl' named entity 'RSV' named entity 'bronchiolitis' named entity 'directly related' named entity 'RT-PCR' named entity 'asthmatic' named entity 'wheezing' named entity 'Mycoplasma pneumoniae' named entity 'bronchiolitis' named entity 'direct immunofluorescence assay' named entity 'pathogens' named entity 'hepatic dysfunction' named entity 'respiratory syncytial virus' named entity 'genetic differences' named entity 'metapneumovirus' named entity 'HPIV' named entity 'hMPV' named entity 'antibiotic' named entity 'correlation' named entity 'bronchiolitis' named entity 'coinfections' named entity 'Clinical characteristics' named entity 'correlation' named entity 'bronchiolitis' named entity 'bronchiolitis' named entity 'clinical characteristics' named entity 'coronaviruses' named entity 'buffered solution' named entity 'RSV' named entity 'pathogens' named entity 'Windows' named entity 'relative humidity' named entity 'Carlsbad, CA' named entity 'fluorescent' named entity 'bronchiolitis' named entity 'human metapneumovirus'

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