About: Clinical Presentation of COVID19 in Dementia Patients

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Clinical Presentation of COVID19 in Dementia Patients
Creator	Bianchetti, Angelo Guerini, F Bianchetti, A Bianchetti, L Boffelli, S Minelli, G Ranieri, P Rozzini, R Trabucchi, M
Source	Medline; PMC
abstract	OBJECTIVE: No studies analyzing the role of dementia as a risk factor for mortality in patients affected by COVID-19. We assessed the prevalence, clinical presentation and outcomes of dementia among subjects hospitalized for COVID19 infection. DESIGN: Retrospective study. SETTING: COVID wards in Acute Hospital in Brescia province, Northern Italy. PARTICIPANTS: We used data from 627 subjects admitted to Acute Medical wards with COVID 19 pneumonia. MEASUREMENTS: Clinical records of each patients admitted to the hospital with a diagnosis of COVID19 infection were retrospectively analyzed. Diagnosis of dementia, modalities of onset of the COVID-19 infection, symptoms of presentation at the hospital and outcomes were recorded. RESULTS: Dementia was diagnosed in 82 patients (13.1%). The mortality rate was 62.2% (51/82) among patients affected by dementia compared to 26.2% (143/545) in subjects without dementia (p<0.001, Chi-Squared test). In a logistic regression model age, and the diagnosis of dementia resulted independently associated with a higher mortality, and patients diagnosed with dementia presented an OR of 1.84 (95% CI: 1.09–3.13, p<0.05). Among patients diagnosed with dementia the most frequent symptoms of onset were delirium, especially in the hypoactive form, and worsening of the functional status. CONCLUSION: The diagnosis of dementia, especially in the most advanced stages, represents an important risk factor for mortality in COVID-19 patients. The clinical presentation of COVID-19 in subjects with dementia is atypical, reducing early recognition of symptoms and hospitalization.
has issue date	2020-05-15(xsd:dateTime)
bibo:doi	10.1007/s12603-020-1389-1
bibo:pmid	32425646
has license	no-cc
sha1sum (hex)	1d79ba2735308cfd7b04687f086942e6d1b7f35a
schema:url	https://doi.org/10.1007/s12603-020-1389-1
resource representing a document's title	Clinical Presentation of COVID19 in Dementia Patients
has PubMed Central identifier	PMC7227170
has PubMed identifier	32425646
schema:publication	J Nutr Health Aging
resource representing a document's body	covid:1d79ba2735308cfd7b04687f086942e6d1b7f35a#body_text
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