About: Phylogenetic and antigenic analysis of avian infectious bronchitis virus in southwestern China, 2012

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About: Phylogenetic and antigenic analysis of avian infectious bronchitis virus in southwestern China, 2012–2016 Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Phylogenetic and antigenic analysis of avian infectious bronchitis virus in southwestern China, 2012–2016
Creator	Huang, Yong Liu, Ping Xia, Jing Cao, San-Jie Du, Li-Jing Han, Xin-Feng He, Xiao Wen, Yi-Ping Yan, Qi-Gui Yao, Ke-Chang
Source	Elsevier; Medline; PMC
abstract	The aim of this study was to decipher the molecular epidemiological and antigenic characteristics of infectious bronchitis virus strains (IBVs) isolated in recent years in southwestern China. A total of 24 field strains were isolated from diseased chickens between 2012 and 2016. Phylogenetic analysis based on S1 nucleotide sequences showed that 16 of the 24 isolates were clustered into four distinct genotypes: QX (37.5%), TW (16.7%, TWI and TWII), Mass (8.3%), and J2 (4.2%). The QX genotype was still the prevalent genotype in southwestern China. Recombination analysis of the S1 subunit gene showed that eight of the 24 field strains were recombinant variants that originated from field strains and vaccine strains. A new potential recombination hotspot [ATTTT(T/A)] was identified, implying that recombination events may become more and more common. The antigenicity of ten IBVs, including seven field strains and commonly used vaccine strains, were assayed with a viral cross-neutralization assay in chicken embryonated kidney cells (CEK). The results showed that the ten IBVs could be divided into four serotypes (Massachusetts, 793B, Sczy3, and SCYB). Sczy3 and 793B were the predominant serotypes. Six of the seven field isolates (all except for cK/CH/SCYB/140913) cross-reacted well with anti-sera against other field strains. In conclusion, the genetic and antigenic features of IBVs from southwestern China in recent years have changed when compared to the previous reports. The results could provide a reference for vaccine development and the prevention of infectious bronchitis in southwestern China.
has issue date	2016-08-13(xsd:dateTime)
bibo:doi	10.1016/j.meegid.2016.08.011
bibo:pmid	27530216
has license	no-cc
sha1sum (hex)	1e9376cfce6209ea7c6dfc8a3106aa0299089ae0
schema:url	https://doi.org/10.1016/j.meegid.2016.08.011
resource representing a document's title	Phylogenetic and antigenic analysis of avian infectious bronchitis virus in southwestern China, 2012–2016
has PubMed Central identifier	PMC7106097
has PubMed identifier	27530216
schema:publication	Infect Genet Evol
resource representing a document's body	covid:1e9376cfce6209ea7c6dfc8a3106aa0299089ae0#body_text
is schema:about of	named entity 'antigenic' named entity 'total' named entity 'field' named entity 'field' named entity 'identified' named entity 'STRAINS' named entity 'CONCLUSION' named entity 'RECOMBINATION HOTSPOT' named entity 'RESULTS' named entity 'GENOTYPES' named entity 'TWI' named entity 'ISOLATES' named entity 'CHANGED' named entity 'COMMON' named entity 'YEARS' named entity 'USED' named entity 'PHYLOGENETIC ANALYSIS' named entity 'EPIDEMIOLOGICAL' named entity 'NUCLEOTIDE SEQUENCES' named entity 'VARIANTS' named entity 'RECOMBINATION' covid:arg/1e9376cfce6209ea7c6dfc8a3106aa0299089ae0 named entity 'SUBUNIT' named entity 'COMPARED' named entity 'REFERENCE' named entity 'VACCINE DEVELOPMENT' named entity 'CELLS' named entity 'EXCEPT FOR' named entity 'CROSS' named entity 'ASSAY' named entity 'SERA' named entity 'SEVEN' named entity 'GENETIC' named entity 'INFECTIOUS BRONCHITIS' named entity 'IDENTIFIED' named entity 'KIDNEY' named entity 'SOUTHWESTERN' named entity 'ANALYSIS' named entity '288' named entity 'PREVIOUS REPORTS' named entity 'PREVENTION OF' named entity 'HAVE' named entity 'NEW' named entity 'DECIPHER' named entity 'MOLECULAR' named entity 'SEROTYPES' named entity 'CHARACTERISTICS' named entity 'CHICKENS' named entity 'GENOTYPE' named entity 'POTENTIAL' named entity 'GENE' named entity 'ISOLATED' named entity 'INCLUDING' named entity 'VIRAL' named entity 'PREDOMINANT' named entity 'SCYB' named entity 'DIVIDED' named entity 'DISEASED' named entity 'MASS' named entity 'RECOMBINANT' named entity 'BASED' named entity 'COULD BE' named entity 'PREVALENT' named entity 'PROVIDE' named entity 'CHICKEN' named entity 'FEATURES' named entity 'VACCINE' named entity 'TOTAL' named entity 'ANTIGENICITY' named entity 'CLUSTERED' named entity 'STUDY' named entity 'DISTINCT'

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