About: Ten-Year Research Update Review: Antiviral Activities from Marine Organisms

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Ten-Year Research Update Review: Antiviral Activities from Marine Organisms
Creator	Coppola, Daniela Costantini, Maria De Pascale, Donatella Lauritano, Chiara Mutalipassi, Mirko Riccio, Gennaro Ruocco, Nadia Zupo, Valerio
Source	Medline; PMC
abstract	Oceans cover more than 70 percent of the surface of our planet and are characterized by huge taxonomic and chemical diversity of marine organisms. Several studies have shown that marine organisms produce a variety of compounds, derived from primary or secondary metabolism, which may have antiviral activities. In particular, certain marine metabolites are active towards a plethora of viruses. Multiple mechanisms of action have been found, as well as different targets. This review gives an overview of the marine-derived compounds discovered in the last 10 years. Even if marine organisms produce a wide variety of different compounds, there is only one compound available on the market, Ara-A, and only another one is in phase I clinical trials, named Griffithsin. The recent pandemic emergency caused by SARS-CoV-2, also known as COVID-19, highlights the need to further invest in this field, in order to shed light on marine compound potentiality and discover new drugs from the sea.
has issue date	2020-07-07(xsd:dateTime)
bibo:doi	10.3390/biom10071007
bibo:pmid	32645994
has license	cc-by
sha1sum (hex)	1febd2ddf45b7c797229858b505d170481e884e8
schema:url	https://doi.org/10.3390/biom10071007
resource representing a document's title	Ten-Year Research Update Review: Antiviral Activities from Marine Organisms
has PubMed Central identifier	PMC7407529
has PubMed identifier	32645994
schema:publication	Biomolecules
resource representing a document's body	covid:1febd2ddf45b7c797229858b505d170481e884e8#body_text
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