About: Maternal COVID-19 infection, clinical characteristics, pregnancy, and neonatal outcome A prospective cohort study

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Maternal COVID-19 infection, clinical characteristics, pregnancy, and neonatal outcome A prospective cohort study
Creator	Antoun, Lina Nashwa, Dr Taweel, El
source	Elsevier; Medline; PMC
abstract	OBJECTIVE: To study the effect of COVID-19 on pregnancy and neonatal outcomes. STUDY DESIGN: Prospective cohort study in a large tertiary maternity unit within a university hospital with an average annual birth of over 10,000 births. We prospectively collected and analysed data for a cohort of 23 pregnant patients including singleton and multiple pregnancies tested positive for COVID-19 between February 2020 and April 2020 inclusive to assess the effect of COVID-19 on pregnancy, and neonatal outcomes. RESULTS: Twenty-three pregnant patients tested positive for COVID-19, delivering 20 babies including a set of twins, with four ongoing pregnancies at the time of manuscript submission. 16/23 (70%) whom tested positive were patients from Asian (Indian sub-continent) background. The severity of the symptoms ranged from mild in 13/23 (65.2%) of the patients, moderate in 2/23 (8.7%), and severe in 8/23 (34.8%). Four out of total 23 COVID-19 pregnant patients (17.4%) developed severe adult respiratory distress syndrome complications requiring ICU support, one of whom led to maternal death 1/23 (4.3%). 11/23 (48%) of the patients had pre-existing co-morbidities, with morbid obesity 5/23 (21.7%) and diabetes 4/23 (17.4%) being the more commonly represented. Of the 23 pregnant patients 19 were in their third trimester of pregnancy and delivered; 7/19 (36.8%) had preterm birth, 3/19 (15.8%) developed adult respiratory distress syndrome before delivery, and 2/19 (10.5%) had pre-eclampsia. 16/19 (84%) of patients delivered by C-section. Out of the 20 new-borns, 18 were singletons with a set of twin. CONCLUSION: COVID-19 is associated with high prevalence of preterm birth, preeclampsia, and caesarean section compared to non-COVID pregnancies. COVID-19 infection was not found in the newborns and none developed severe neonatal complications.
has issue date	2020-07-15(xsd:dateTime)
bibo:doi	10.1016/j.ejogrb.2020.07.008
bibo:pmid	32732059
has license	no-cc
sha1sum (hex)	200b0c84847c1f338e66189a328248bcc5de3477
schema:url	https://doi.org/10.1016/j.ejogrb.2020.07.008
resource representing a document's title	Maternal COVID-19 infection, clinical characteristics, pregnancy, and neonatal outcome A prospective cohort study
has PubMed Central identifier	PMC7362841
has PubMed identifier	32732059
schema:publication	Eur J Obstet Gynecol Reprod Biol
resource representing a document's body	covid:200b0c84847c1f338e66189a328248bcc5de3477#body_text
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