About: A long-term animal experiment indicating persistent infection of bovine coronavirus in cattle

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	A long-term animal experiment indicating persistent infection of bovine coronavirus in cattle
Creator	Hatama, Shinichi Ishihara, Ryoko Kanno, Toru Uchida, Ikuo
Source	Medline; PMC
abstract	A long-term animal experiment involving inoculation with bovine coronavirus (BCoV) was conducted to verify its persistent infection in cattle. Three colostrum-deprived Holstein calves were housed separately in individual rooms of a high-containment facility and inoculated with the BCoV strain Kumamoto/1/07. Until the end of the experiment (1,085, 700 and 280 days, respectively), viral RNAs were detected sporadically by RT-PCR and nested PCR from plasma, nasal discharge, and feces. Seroconversion and titer changes were validated by hemagglutination inhibition tests and neutralization tests. Among the samples, nasal discharge showed a higher viral positivity than feces, which seemed to be associated with positive detection in the plasma. These data demonstrate the existence of persistent infection of BCoV in the respiratory tissues of cattle.
has issue date	2018-05-18(xsd:dateTime)
bibo:doi	10.1292/jvms.18-0050
bibo:pmid	29780039
has license	cc-by-nc-nd
sha1sum (hex)	2041dc24bd4022a90b0b441ed6f1024f3e16dc77
schema:url	https://doi.org/10.1292/jvms.18-0050
resource representing a document's title	A long-term animal experiment indicating persistent infection of bovine coronavirus in cattle
has PubMed Central identifier	PMC6068295
has PubMed identifier	29780039
schema:publication	J Vet Med Sci
resource representing a document's body	covid:2041dc24bd4022a90b0b441ed6f1024f3e16dc77#body_text
is schema:about of	named entity 'NOTE' named entity 'ITS' named entity 'HIGH' named entity 'HEMAGGLUTINATION INHIBITION TESTS' named entity 'STRAIN' named entity '2F1' named entity 'NASAL DISCHARGE' named entity 'ASSOCIATED WITH' named entity 'TITER' named entity 'SAMPLES' named entity 'END' named entity 'DETECTED' named entity 'RNAS' named entity 'tests' named entity 'infection' named entity 'animal' named entity 'Three' named entity 'calves' named entity 'ANIMAL EXPERIMENT' named entity 'BOVINE CORONAVIRUS' named entity 'NEUTRALIZATION TESTS' named entity 'ROOMS' named entity 'FACILITY' named entity 'FECES' named entity 'VERIFY' named entity 'DETECTION' named entity 'CALVES' named entity 'INDICATING' named entity 'CATTLE' named entity 'LONG-TERM' named entity 'PERSISTENT INFECTION' named entity 'BOVINE CORONAVIRUS' named entity 'SPORADICALLY' named entity 'PLASMA' named entity 'DATA' named entity 'COLOSTRUM' named entity 'VIRAL' named entity 'CONTAINMENT' named entity 'PERSISTENT INFECTION' named entity 'POSITIVE' named entity 'ANIMAL EXPERIMENT' named entity 'INOCULATION' named entity 'INDIVIDUAL' named entity 'TISSUES' named entity 'HOLSTEIN' named entity 'HOUSED' named entity '700' named entity 'RT-PCR' named entity 'VALIDATED' named entity 'THESE' named entity 'SEROCONVERSION' named entity 'NESTED PCR ' named entity 'INVOLVING' named entity 'CHANGES' named entity 'EXPERIMENT' named entity 'CATTLE' named entity 'RESPIRATORY' named entity 'LONG-TERM' named entity 'DAYS' covid:arg/2041dc24bd4022a90b0b441ed6f1024f3e16dc77 named entity 'individual' named entity 'Holstein' named entity 'persistent' named entity 'neutralization tests' named entity 'Holstein calves' named entity 'plasma' named entity 'nasal discharge' named entity 'long-term' named entity 'hemagglutination inhibition' named entity 'cattle' named entity 'nasal discharge' named entity 'RT-PCR' named entity 'nested PCR' named entity 'animal experiment' named entity 'BCoV' named entity 'infection' named entity 'long-term' named entity 'existence'

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