About: Tackling SARS-CoV-2: proposed targets and repurposed drugs

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Tackling SARS-CoV-2: proposed targets and repurposed drugs
Creator	Degani, Mariam Joshi, Maithili Joshi, Siddhi
source	Medline; PMC
abstract	The SARS-CoV-2 pandemic, declared as a global health emergency by the WHO in February 2020, has currently infected more than 6 million people with fatalities near 371,000 and increasing exponentially, in absence of vaccines and drugs. The pathogenesis of SARS-CoV-2 is still being elucidated. Identifying potential targets and repurposing drugs as therapeutic options is the need of the hour. In this review, we focus on potential druggable targets and suitable therapeutics, currently being explored in clinical trials, to treat SARS-CoV-2 infection. A brief understanding of the complex interactions of both viral as well as host targets, and the possible repurposed drug candidates are described with an emphasis on understanding the mechanisms at the molecular level.
has issue date	2020-06-22(xsd:dateTime)
bibo:doi	10.4155/fmc-2020-0147
bibo:pmid	32564623
has license	cc-by
sha1sum (hex)	205fd16be9dae9a0a5b4ebf020a154a9b3fb3610
schema:url	https://doi.org/10.4155/fmc-2020-0147
resource representing a document's title	Tackling SARS-CoV-2: proposed targets and repurposed drugs
has PubMed Central identifier	PMC7307730
has PubMed identifier	32564623
schema:publication	Future medicinal chemistry
resource representing a document's body	covid:205fd16be9dae9a0a5b4ebf020a154a9b3fb3610#body_text
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