About: A rapid review of evidence and recommendations from the SIOPE Radiation Oncology working group to help mitigate for reduced paediatric radiotherapy capacity during the COVID-19 pandemic or other crises

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About: A rapid review of evidence and recommendations from the SIOPE Radiation Oncology working group to help mitigate for reduced paediatric radiotherapy capacity during the COVID-19 pandemic or other crises Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	A rapid review of evidence and recommendations from the SIOPE Radiation Oncology working group to help mitigate for reduced paediatric radiotherapy capacity during the COVID-19 pandemic or other crises
Creator	Ajithkumar, Thankamma Alapetite, Claire Boterberg, Tom Dieckmann, Karin Gandola, Lorenza Horan, Gail Janssens, Geert Lassen-Ramshad, Yasmin Maduro, John Mandeville, Henry Padovani, Laetitia Ruebe, Christian Thorp, Nicky Timmermann, Beate
Source	Elsevier; Medline; PMC
abstract	Abstract Objective To derive evidence-based recommendations for the optimal utilisation of resources during unexpected shortage of radiotherapy capacity. Methods and materials We have undertaken a rapid review of published literature on the role of radiotherapy in the multimodality treatment of paediatric cancers governing the European practice of paediatric radiotherapy. The derived data has been discussed with expert paediatric radiation oncologists to derive a hierarchy of recommendations. Results The general recommendations to mitigate the potential detriment of an unexpected shortage of radiotherapy facilities include: (1) maintain current standards of care as long as possible (2) refer to another specialist paediatric radiotherapy department with similar level of expertise (3) prioritise use of existing radiotherapy resources to treat patients with tumours where radiotherapy has the most effect on clinical outcome (4) use chemotherapy to defer the start of radiotherapy where timing of radiotherapy is not expected to be detrimental (5) active surveillance for low-grade tumours if appropriate and (6) consider iso-effective hypofractionated radiotherapy regimens only for selected patients with predicted poor prognosis. The effectiveness of radiotherapy and recommendations for prioritisation of its use for common and challenging paediatric tumours are discussed. Conclusion This review provides evidence-based treatment recommendations during unexpected shortage of paediatric radiotherapy facilities. It has wider applications for the optimal utilization of facilities, to improve clinical outcome in low- and middle-income countries, where limited resources continue to be a challenge.
has issue date	2020-04-27(xsd:dateTime)
bibo:doi	10.1016/j.radonc.2020.04.035
bibo:pmid	32342872
has license	els-covid
sha1sum (hex)	207e8385634d4b5aa62cacb7abf4fa077a810c46
schema:url	https://doi.org/10.1016/j.radonc.2020.04.035
resource representing a document's title	A rapid review of evidence and recommendations from the SIOPE Radiation Oncology working group to help mitigate for reduced paediatric radiotherapy capacity during the COVID-19 pandemic or other crises
has PubMed Central identifier	PMC7184972
has PubMed identifier	32342872
schema:publication	Radiother Oncol
resource representing a document's body	covid:207e8385634d4b5aa62cacb7abf4fa077a810c46#body_text
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