About: Innate immune response to arenaviral infection: a focus on the highly pathogenic New World hemorrhagic arenaviruses

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About: Innate immune response to arenaviral infection: a focus on the highly pathogenic New World hemorrhagic arenaviruses Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Innate immune response to arenaviral infection: a focus on the highly pathogenic New World hemorrhagic arenaviruses
Creator	Paessler, Slobodan Huang, Cheng Koma, Takaaki Kolokoltsova, Olga Brasier, Allan
Source	Elsevier; Medline; PMC
abstract	Arenaviruses are enveloped, negative-stranded RNA viruses that belong to the family Arenaviridae. This diverse family can be further classified into OW (Old World) and NW (New World) arenaviruses based on their antigenicity, phylogeny, and geographical distribution. Many of the NW arenaviruses are highly pathogenic viruses that cause systemic human infections characterized by hemorrhagic fever and/or neurological manifestations, constituting public health problems in their endemic regions. NW arenavirus infection induces a variety of host innate immune responses, which could contribute to the viral pathogenesis and/or influence the final outcome of virus infection in vitro as well as in vivo. On the other hand, NW arenaviruses have also developed several strategies to counteract the host innate immune response. We will review current knowledge regarding the interplay between the host innate immune response and NW arenavirus infection in vitro and in vivo, with emphasis on viral-encoded proteins and their effect on the type I interferon response.
has issue date	2013-12-01(xsd:dateTime)
bibo:doi	10.1016/j.jmb.2013.09.028
bibo:pmid	24075870
has license	green-oa
sha1sum (hex)	20e132bcb171957780e3a30075ae991dc91c0bb3
schema:url	https://doi.org/10.1016/j.jmb.2013.09.028
resource representing a document's title	Innate immune response to arenaviral infection: a focus on the highly pathogenic New World hemorrhagic arenaviruses
has PubMed Central identifier	PMC3864108
has PubMed identifier	24075870
schema:publication	Journal of Molecular Biology
resource representing a document's body	covid:20e132bcb171957780e3a30075ae991dc91c0bb3#body_text
is schema:about of	named entity 'FOCUS' named entity 'This' named entity 'host' named entity 'innate immune response' named entity 'influence' named entity 'Immune' named entity 'Infection' named entity 'INFECTION' named entity 'NEW' named entity 'PATHOGENIC' named entity 'CLASSIFIED' named entity 'INFLUENCE' named entity 'VIRUSES' named entity 'ENDEMIC' named entity 'CAUSE' named entity 'STRATEGIES' named entity 'REGIONS' named entity 'HIGHLY' named entity 'IN VITRO' named entity 'RESPONSE TO' named entity 'HOST' named entity 'HEMORRHAGIC FEVER' named entity 'IMMUNE RESPONSES' named entity 'KNOWLEDGE' named entity 'ARENAVIRUSES' named entity 'ANTIGENICITY' named entity 'HUMAN' named entity 'VIRUS INFECTION' named entity 'SYSTEMIC' named entity 'THEIR' named entity 'CONTRIBUTE ' named entity 'BASED' named entity 'DIVERSE' named entity 'RNA VIRUSES' named entity 'VIRAL PATHOGENESIS' named entity 'CHARACTERIZED' named entity 'ARENAVIRUS INFECTION' named entity 'INFECTIONS' named entity 'EFFECT' named entity 'OUTCOME' named entity 'INTERFERON ' named entity 'WORLD' named entity 'INNATE IMMUNE RESPONSE' named entity 'VARIETY' named entity 'PHYLOGENY' named entity 'INNATE IMMUNE RESPONSE' named entity 'WORLD' named entity 'PUBLIC HEALTH' named entity 'TYPE I INTERFERON' named entity 'ENCODED' named entity 'NEUROLOGICAL MANIFESTATIONS' named entity 'FINAL' named entity 'PATHOGENIC' named entity 'HIGHLY' named entity 'IN VIVO' named entity 'CURRENT' named entity 'NEGATIVE' named entity 'PROTEINS' named entity 'FAMILY' named entity 'GEOGRAPHICAL DISTRIBUTION' named entity 'HAND' named entity 'REVIEW' named entity 'RESPONSE' named entity 'PROBLEMS' named entity 'ARENAVIRUSES' named entity 'HAVE' named entity 'HEMORRHAGIC' named entity 'ARENAVIRIDAE' named entity 'virus' named entity 'antigenicity' named entity 'infections' named entity 'type I interferon' named entity 'variety' named entity 'phylogeny' named entity 'hemorrhagic fever' named entity 'neurological' named entity 'arenavirus'

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