About: A pantropic canine coronavirus genetically related to the prototype isolate CB/05()

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About: A pantropic canine coronavirus genetically related to the prototype isolate CB/05() Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	A pantropic canine coronavirus genetically related to the prototype isolate CB/05()
Creator	Buonavoglia, Canio Decaro, Nicola Elia, Gabriella Mari, Viviana Martella, Vito Cirone, Francesco Caramelli, Maria Di Bello, Antonio Varello, Katia Zhang, Shucheng Lucente, Maria King, Vickie Von Reitzenstein, Marcela
Source	Elsevier; Medline; PMC
abstract	We report the genetic and biological characterisation of a novel pantropic canine coronavirus (CCoV), strain 450/07, which caused the death of a 60-day-old miniature pinscher. At the genetic level, this virus was strictly related to the prototype strain CB/05, but displayed some unique features. After experimental infection with the new pantropic isolate, most inoculated dogs showed diarrhoea and acute lymphopenia. Gross lesions and histological changes were mainly evident in the gut and lymphoid tissues, although some animals showed remarkable changed also in parenchymatous organs. The viral RNA was detected in the faeces and/or internal organs of most pups. These findings seem to indicate that strain 450/07 is able to spread to internal organs (mainly lymphoid tissues), causing lymphopenia but inducing a mild disease.
has issue date	2012-09-14(xsd:dateTime)
bibo:doi	10.1016/j.vetmic.2012.03.039
bibo:pmid	22542271
has license	no-cc
sha1sum (hex)	211c0222f69ae8e89956e86bcdcde1fcc628e957
schema:url	https://doi.org/10.1016/j.vetmic.2012.03.039
resource representing a document's title	A pantropic canine coronavirus genetically related to the prototype isolate CB/05()
has PubMed Central identifier	PMC7117425
has PubMed identifier	22542271
schema:publication	Vet Microbiol
resource representing a document's body	covid:211c0222f69ae8e89956e86bcdcde1fcc628e957#body_text
is schema:about of	named entity 'LYMPHOID TISSUES' named entity 'DISPLAYED' named entity 'LEVEL' named entity 'MINIATURE PINSCHER' named entity 'CANINE CORONAVIRUS' named entity 'CAUSING' named entity 'NEW' named entity 'RELATED' named entity 'STRAIN' named entity '450' named entity 'FAECES' named entity 'CAUSED' named entity 'inoculated' named entity 'infection' named entity 'VIRAL RNA' named entity 'DIARRHOEA' named entity 'UNIQUE' named entity 'TO INDICATE' named entity 'DAY-OLD' named entity 'DEATH' named entity 'INTERNAL' named entity 'FINDINGS' named entity 'MILD DISEASE' named entity 'EXPERIMENTAL INFECTION' named entity 'REPORT' named entity 'FEATURES' named entity 'DETECTED' named entity 'DOGS' named entity 'SPREAD' named entity 'VIRUS' named entity 'CHANGED' named entity 'PUPS' named entity 'NOVEL' named entity 'LYMPHOPENIA' named entity 'BUT' named entity 'THESE' named entity 'PROTOTYPE' named entity 'BIOLOGICAL' named entity 'ISOLATE' named entity 'ORGANS' named entity 'HISTOLOGICAL' named entity 'GENETIC' named entity 'THE GUT' named entity 'INDUCING' named entity 'ACUTE' named entity 'GROSS LESIONS' named entity 'ANIMALS' named entity 'CHANGES' covid:arg/211c0222f69ae8e89956e86bcdcde1fcc628e957 named entity 'changed' named entity 'lesions' named entity 'internal organs' named entity 'dogs' named entity 'pups' named entity 'prototype' named entity 'lymphopenia' named entity 'Coronaviruses' named entity 'sterility' named entity 'body weight' named entity 'RNA' named entity 'genus' named entity 'organs' named entity 'RNA' named entity 'lymphoid tissues' named entity 'lymphopenia' named entity 'genetic level' named entity 'internal organs' named entity 'strain' named entity 'coronaviruses'

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