About: Does atopy affect the course of viral pneumonia?

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Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Does atopy affect the course of viral pneumonia?
Creator	Espa, Sociedad Bingöl, A Bostancı, I Can, D Erdem, S Erge, D Ersu, R Girit, S Pekcan, S Yüksel, H
source	Elsevier; Medline; PMC
abstract	Abstract Background The presence of atopy is considered as a risk factor for severe respiratory symptoms in children. The objective of this study was to examine the effect of atopy on the course of disease in children hospitalised with viral pneumonia. Methods Children between the ages of 1 and 6 years hospitalised due to viral pneumonia between the years of 2013 and 2016 were included to this multicentre study. Patients were classified into two groups as mild–moderate and severe according to the course of pneumonia. Presence of atopy was evaluated with skin prick tests. Groups were compared to evaluate the risk factors associated with severe viral pneumonia. Results A total of 280 patients from nine centres were included in the study. Of these patients, 163 (58.2%) were male. Respiratory syncytial virus (29.7%), Influenza A (20.5%), rhinovirus (18.9%), adenovirus (10%), human metapneumovirus (8%), parainfluenza (5.2%), coronavirus (6%), and bocavirus (1.6%) were isolated from respiratory samples. Eighty-five (30.4%) children had severe pneumonia. Atopic sensitisation was found in 21.4% of the patients. Ever wheezing (RR: 1.6, 95% CI: 1.1–2.4), parental asthma (RR: 1.5, 95% CI: 1.1–2.2), other allergic diseases in the family (RR: 1.8, 95% CI: 1.2–2.9) and environmental tobacco smoke (RR: 1.6, 95% CI: 1.1–3.5) were more common in the severe pneumonia group. Conclusions When patients with mild–moderate pneumonia were compared to patients with severe pneumonia, frequency of atopy was not different between the two groups. However, parental asthma, ever wheezing and environmental tobacco smoke exposure are risk factors for severe viral pneumonia in children.
has issue date	2018-04-30(xsd:dateTime)
bibo:doi	10.1016/j.aller.2017.04.003
bibo:pmid	28634031
has license	els-covid
sha1sum (hex)	21a9176cb0fbcb9030373b1bda68d3c8f0f2a2ed
schema:url	https://doi.org/10.1016/j.aller.2017.04.003
resource representing a document's title	Does atopy affect the course of viral pneumonia?
has PubMed Central identifier	PMC7130674
has PubMed identifier	28634031
schema:publication	Allergologia et Immunopathologia
resource representing a document's body	covid:21a9176cb0fbcb9030373b1bda68d3c8f0f2a2ed#body_text
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