About: Tropheryma whipplei in Children with Gastroenteritis

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Tropheryma whipplei in Children with Gastroenteritis
Creator	Raoult, Didier Rolain, Jean-Marc Fenollar, Florence Bosdure, Emmanuelle Garnier, Jean-Marc Li, Wenjun Minodier, Philippe Richet, Hervé Li, W Raoult, D Bosdure, E De La Timone, Hôpital Fenollar, F Garnier, J.-M Minodier, Phillippe Nord, Hôpital Pôle De Mal-Adies Infectieuses, ; Raoult, ( Richet, H Rolain, J.-M Vega, Charles
Source	Medline; PMC
abstract	Tropheryma whipplei, which causes Whipple disease, is found in human feces and may cause gastroenteritis. To show that T. whipplei causes gastroenteritis, PCRs for T. whipplei were conducted with feces from children 2–4 years of age. Western blotting was performed for samples from children with diarrhea who had positive or negative results for T. whipplei. T. whipplei was found in samples from 36 (15%) of 241 children with gastroenteritis and associated with other diarrheal pathogens in 13 (33%) of 36. No positive specimen was detected for controls of the same age (0/47; p = 0.008). Bacterial loads in case-patients were as high as those in patients with Whipple disease and significantly higher than those in adult asymptomatic carriers (p = 0.002). High incidence in patients and evidence of clonal circulation suggests that some cases of gastroenteritis are caused or exacerbated by T. whipplei, which may be co-transmitted with other intestinal pathogens.
has issue date	2010-05-01(xsd:dateTime)
bibo:doi	10.3201/eid1605.091801
bibo:pmid	20409366
has license	no-cc
sha1sum (hex)	23f71cec67b168779d76b16f771126d98fc6f22e
schema:url	https://doi.org/10.3201/eid1605.091801
resource representing a document's title	Tropheryma whipplei in Children with Gastroenteritis
has PubMed Central identifier	PMC2954008
has PubMed identifier	20409366
schema:publication	Emerg Infect Dis
resource representing a document's body	covid:23f71cec67b168779d76b16f771126d98fc6f22e#body_text
is schema:about of	named entity 'PCR' named entity 'Whipple disease' named entity 'Roche Diagnostics' named entity 'PCR' named entity 'rotavirus' named entity 'Whipple disease' named entity 'incubation' named entity 'polyacrylamide gel electrophoresis' named entity 'μmol' named entity 'incubation' named entity 'Yersinia' named entity 'continuing medical education' named entity 'continuing medical education' named entity 'PCR' named entity 'Bacteria' named entity 'coronavirus' named entity 'Medscape' named entity 'gastroenteritis' named entity 'Whipple disease' named entity 'gastroenteritis' named entity 'PCR' named entity 'feces' named entity 'gastroenteritis' named entity 'pmol' named entity 'gastroenteritis' named entity 'France' named entity 'pathogens' named entity 'Genotyping' named entity 'infection' named entity 'negative staining' named entity '0.45' named entity 'Whipple disease' named entity 'gastroenteritis' named entity 'IgM' named entity 'Africa' named entity 'Western blotting' named entity 'fecal-oral' named entity 'epidemiologic' named entity 'PCR' named entity 'clone' named entity 'electron microscopy' named entity 'quantitative PCR' named entity 'genotype' named entity 'Western blotting' named entity 'Nitrocellulose' named entity 'primers' named entity 'pathogens' named entity 'control group' named entity 'Fisher exact test' named entity 'gastroenteritis' named entity 'primers' named entity '36 children' named entity 'control group' named entity 'chromatographic' named entity 'quantitative PCR' named entity '7 girls' named entity 'microaerophilic' named entity 'saliva' named entity 'PCR' named entity 'adenovirus' named entity 'protein'

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