About: Prevalence of comorbidities in cases of Middle East respiratory syndrome coronavirus: a retrospective study

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About: Prevalence of comorbidities in cases of Middle East respiratory syndrome coronavirus: a retrospective study Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Prevalence of comorbidities in cases of Middle East respiratory syndrome coronavirus: a retrospective study
Creator	Mohamed, N Abanmy, N Alanazi, M Aleanizy, F Alhawassi, T Ali, R Alqahtani, F Alrasheed, M Fs, Aleanizy Fy, Alqahtani Hadi Mohamed, El Hadi, Ali Ms, Alanazi
Source	Medline; PMC
abstract	The Middle East respiratory syndrome coronavirus (MERS-CoV) is a life-threatening respiratory disease with a high case fatality rate; however, its risk factors remain unclear. We aimed to explore the influence of demographic factors, clinical manifestations and underlying comorbidities on mortality in MERS-CoV patients. Retrospective chart reviews were performed to identify all laboratory-confirmed cases of MERS-COV infection in Saudi Arabia that were reported to the Ministry of Health of Saudi Arabia between 23 April 2014 and 7 June 2016. Statistical analyses were conducted to assess the effect of sex, age, clinical presentation and comorbidities on mortality from MERS-CoV. A total of 281 confirmed MERS-CoV cases were identified: 167 (59.4%) patients were male and 55 (20%) died. Mortality predominantly occurred among Saudi nationals and older patients and was significantly associated with respiratory failure and shortness of breath. Of the 281 confirmed cases, 160 (56.9%) involved comorbidities, wherein diabetes mellitus, hypertension, ischemic heart disease, congestive heart failure, end-stage renal disease and chronic kidney disease were significantly associated with mortality from MERS-CoV and two or three comorbidities significantly affected the fatality rates from MERS-CoV. The findings of this study show that old age and the existence of underlying comorbidities significantly increase mortality from MERS-CoV.
has issue date	2018-11-05(xsd:dateTime)
bibo:doi	10.1017/s0950268818002923
bibo:pmid	30394248
has license	cc-by
sha1sum (hex)	24de2f3f8107492057953a49ec7182514e9ff95a
schema:url	https://doi.org/10.1017/s0950268818002923
resource representing a document's title	Prevalence of comorbidities in cases of Middle East respiratory syndrome coronavirus: a retrospective study
has PubMed Central identifier	PMC6518603
has PubMed identifier	30394248
schema:publication	Epidemiol Infect
resource representing a document's body	covid:24de2f3f8107492057953a49ec7182514e9ff95a#body_text
is schema:about of	named entity 'EPIDEMIOLOGY' named entity '2016' named entity 'involved' named entity 'confirmed' named entity 'MERS-CoV' named entity 'comorbidities' named entity 'CASES' named entity 'INFECTION PREVALENCE' covid:arg/24de2f3f8107492057953a49ec7182514e9ff95a named entity 'SEX' named entity 'UNDERLYING' named entity 'CASES' named entity '2856' named entity 'HEALTH' named entity 'JUNE' named entity 'RESPIRATORY DISEASE' named entity 'DIABETES MELLITUS' named entity 'MALE' named entity 'ASSESS' named entity 'CONGESTIVE HEART FAILURE' named entity 'APRIL' named entity 'SAUDI ARABIA' named entity 'IS A' named entity 'MORTALITY' named entity 'RETROSPECTIVE' named entity 'END-STAGE RENAL DISEASE' named entity 'PATIENTS' named entity 'HIGH' named entity 'COMORBIDITIES' named entity 'CONFIRMED' named entity 'DEMOGRAPHIC FACTORS' named entity 'OCCURRED' named entity 'AFFECTED' named entity 'LABORATORY' named entity 'RETROSPECTIVE STUDY' named entity 'MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS' named entity 'ASSOCIATED WITH' named entity 'LIFE' named entity 'CHART REVIEWS' named entity 'SHORTNESS OF BREATH' named entity '2859' named entity 'INFECTION' named entity 'OLD AGE' named entity 'CLINICAL MANIFESTATIONS' named entity 'CASE FATALITY RATE' named entity 'PERFORMED' named entity '160' named entity 'RISK FACTORS' named entity 'TO IDENTIFY' named entity 'STATISTICAL ANALYSES' named entity 'DIED' named entity 'HYPERTENSION' named entity 'SAUDI' named entity 'ISCHEMIC HEART DISEASE' named entity 'INCREASE' named entity 'STUDY' named entity 'AGE' named entity 'CHRONIC KIDNEY DISEASE' named entity 'INFLUENCE' named entity 'FINDINGS' named entity 'ITS' named entity 'COMORBIDITIES' named entity 'RATES' named entity 'RESPIRATORY FAILURE' named entity 'TOTAL' named entity 'EFFECT' named entity 'UNCLEAR' named entity '167' named entity 'MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS'

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