About: Chapter Fifteen Nasal Vaccine Delivery

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Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Chapter Fifteen Nasal Vaccine Delivery
Creator	Arumugam, M Chakrabarti, S Jaganathan, K Ramvikas, M
Source	Elsevier; PMC
abstract	Abstract The mucosal surfaces represent the major site of entry of many pathogens, and major challenges in vaccine development include safety and stability in a suitable dosage form. Micro- and nanocarrier-based delivery systems as nasal vaccines induce humoral, cellular, and mucosal immunity. The nasal route of vaccination could also offer immunity at several distant mucosal sites (oral, rectal, vaginal, and pulmonary), which is considered a simplified and cost-effective mode of vaccination with enhanced patient compliance. Most of the nasal vaccine delivery systems in the form of microparticulates, nanoparticulates, and liposomes are currently under development and prove to offer immunity in animal models. The importance and potential of the nasal route of administration for vaccines is unexplored, and this chapter outlines the opportunities, challenges, and potential delivery solutions to facilitate the development of improved nasal vaccines for infectious diseases.
has issue date	2017-12-31(xsd:dateTime)
bibo:doi	10.1016/b978-0-323-39981-4.00015-4
has license	els-covid
sha1sum (hex)	25648bfa058251582d196e648d4ebd78ce1ff384
schema:url	https://doi.org/10.1016/b978-0-323-39981-4.00015-4
resource representing a document's title	Chapter Fifteen Nasal Vaccine Delivery
has PubMed Central identifier	PMC7151830
schema:publication	Micro and Nanotechnology in Vaccine Development
resource representing a document's body	covid:25648bfa058251582d196e648d4ebd78ce1ff384#body_text
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