About: Outcomes from COVID-19 across the range of frailty: excess mortality in fitter older people

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Outcomes from COVID-19 across the range of frailty: excess mortality in fitter older people
Creator	Davis, Daniel Knopp, Paul Mannan, Imran Mcloughlin, Benjamin Miles, Amy Rather, Arshad Webb, Thomas
Source	MedRxiv
abstract	Purpose Our aim was to quantify the mortality from COVID-19 and identify any interactions with frailty and other demographic factors. Methods Hospitalised patients aged [≥]70 were included, comparing COVID-19 cases with non-COVID-19 controls admitted over the same period. Frailty was prospectively measured and mortality ascertained through linkage with national and local statutory reports. Results In 217 COVID-19 cases and 160 controls, older age and South Asian ethnicity, though not socioeconomic position, were associated with higher mortality. For frailty, differences in effect size were evident between cases (HR 1.02, 95%CI 0.93-1.12) and controls (HR 1.99, 95%CI 1.46-2.72), with an interaction term (HR 0.51, 95%CI 0.37-0.71) in multivariable models. Conclusions Our findings suggest that (i) frailty is not a good discriminator of prognosis in COVID-19 and (ii) pathways to mortality may differ in fitter compared with frailer older patients.
has issue date	2020-05-24(xsd:dateTime)
bibo:doi	10.1101/2020.05.22.20110486
has license	medrxiv
sha1sum (hex)	25c65262de8d0decbc84fc575b7602517e1bbe6a
schema:url	https://doi.org/10.1101/2020.05.22.20110486
resource representing a document's title	Outcomes from COVID-19 across the range of frailty: excess mortality in fitter older people
resource representing a document's body	covid:25c65262de8d0decbc84fc575b7602517e1bbe6a#body_text
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