About: Antigenicity of structural components from porcine transmissible gastroenteritis virus

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Antigenicity of structural components from porcine transmissible gastroenteritis virus
Creator	Garwes, D Cartwright, S Higgins, D Lucas, M Pike, B
source	PMC
abstract	Pregnant sows were inoculated with inactivated transmissible gastroenteritis virus and with preparations of virus surface projections and subviral particles derived by detergent treatment of the virus. Neutralising antibody was demonstrated in serum and colostrum from animals that received whole virus or preparations of surface projections whereas subviral particles failed to stimulate neutralising antibody formation. Similar results were obtained with serum from rabbits inoculated with whole virus and structural components. All three preparations stimulated the formation of agglutinating antibodies, as demonstrated by sedimentation analysis and filtration studies with radiolabelled virus. The immunoglobulin classes responsible for neutralising antibody activity in sows inoculated by the intramammary route were examined. In each case where the immunoglobulin class was determined, IgG was found. One sow that received surface projections also had IgA with neutralising activity in her colostrum. In contrast, infection of sows with live whole virus resulted in neutralising antibody of the IgG, IgM and IgA classes.
has issue date	2002-11-13(xsd:dateTime)
bibo:doi	10.1016/0378-1135(79)90034-8
has license	no-cc
sha1sum (hex)	261c9158a7f08cb5c965b6a78821ad658b84474e
schema:url	https://doi.org/10.1016/0378-1135%2879%2990034-8
resource representing a document's title	Antigenicity of structural components from porcine transmissible gastroenteritis virus
has PubMed Central identifier	PMC7117557
schema:publication	Vet Microbiol
resource representing a document's body	covid:261c9158a7f08cb5c965b6a78821ad658b84474e#body_text
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