About: MicroRNA miR-320a and miR-140 inhibit mink enteritis virus infection by repression of its receptor, feline transferrin receptor

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About: MicroRNA miR-320a and miR-140 inhibit mink enteritis virus infection by repression of its receptor, feline transferrin receptor Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	MicroRNA miR-320a and miR-140 inhibit mink enteritis virus infection by repression of its receptor, feline transferrin receptor
Creator	Wang, Shuang Li, Zhili Hou, Qiang Liu, Weiquan Mao, Yaping Wang, Jigui Yi, Bao Yuan, Daoli Sun, Jia-Zeng
Source	Medline; PMC
abstract	Mink enteritis virus (MEV) is one of the most important pathogens in the mink industry. Recent studies have shed light into the role of microRNAs (miRNAs), small noncoding RNAs of length ranging from 18–23 nucleotides (nt), as critical modulators in the host-pathogen interaction networks. We previously showed that miRNA miR-181b can inhibit MEV replication by repression of viral non-structural protein 1 expression. Here, we report that two other miRNAs (miR-320a and miR-140) inhibit MEV entry into feline kidney (F81) cells by downregulating its receptor, transferrin receptor (TfR), by targeting the 3′ untranslated region (UTR) of TfR mRNA, while being themselves upregulated.
has issue date	2014-12-03(xsd:dateTime)
bibo:doi	10.1186/s12985-014-0210-3
bibo:pmid	25465595
has license	cc-by
sha1sum (hex)	26ba0cb6190e2a4b476ebf7122a0e439bbe80229
schema:url	https://doi.org/10.1186/s12985-014-0210-3
resource representing a document's title	MicroRNA miR-320a and miR-140 inhibit mink enteritis virus infection by repression of its receptor, feline transferrin receptor
has PubMed Central identifier	PMC4264318
has PubMed identifier	25465595
schema:publication	Virol J
resource representing a document's body	covid:26ba0cb6190e2a4b476ebf7122a0e439bbe80229#body_text
is schema:about of	named entity 'RECEPTOR' named entity 'feline' named entity 'length' named entity 'replication' named entity 'downregulating' named entity 'inhibit' named entity 'miRNA' named entity 'REPRESSION' named entity 'TRANSFERRIN RECEPTOR' named entity 'REPORT' named entity 'HOST-PATHOGEN INTERACTION' named entity 'MICRORNA' named entity 'MEV' named entity 'HERE' named entity 'MIR-181B' named entity 'MIRNAS' named entity 'UPREGULATED' named entity 'RNAS' named entity 'REPLICATION' named entity 'LENGTH' named entity 'TRANSFERRIN RECEPTOR' named entity 'MICRORNAS' named entity 'MIR' named entity 'ITS' named entity 'MIR-140' named entity 'VIRUS INFECTION' named entity 'MINK ENTERITIS VIRUS' named entity 'ROLE' named entity 'NON-STRUCTURAL PROTEIN 1' named entity 'ITS' named entity 'ONE OF' named entity 'BEING' named entity 'FELINE' named entity 'TFR' named entity 'IMPORTANT' named entity 'EXPRESSION' named entity 'REPRESSION' named entity 'MODULATORS' named entity 'UNTRANSLATED REGION' named entity 'MIR-140' named entity 'LIGHT' named entity 'CRITICAL' named entity 'PATHOGENS' named entity 'NUCLEOTIDES' named entity 'STUDIES' named entity 'MIRNA' named entity 'RECENT' named entity 'SMALL' named entity 'TARGETING' named entity 'PREVIOUSLY' named entity 'NETWORKS' named entity 'MINK ENTERITIS VIRUS' named entity 'VIRAL' named entity 'MRNA' named entity 'KIDNEY' named entity 'MINK' named entity 'RECEPTOR' named entity '80%' named entity 'INDUSTRY' named entity 'FELINE' named entity 'ENTRY' named entity 'HAVE' named entity 'CELLS' named entity 'Recent' named entity 'miRNAs' named entity 'genomic DNA' named entity 'primary infection' named entity 'MEV' named entity 'vector' named entity '3′UTR' named entity 'miRNAs' named entity 'MEV' named entity 'feline panleukopenia virus'

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