About: Rhinovirus-induced wheezing in infancy—the first sign of childhood asthma?

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About: Rhinovirus-induced wheezing in infancy—the first sign of childhood asthma? Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Rhinovirus-induced wheezing in infancy—the first sign of childhood asthma?
Creator	Korppi, Matti Waris, Matti Korhonen, Kaj Kotaniemi-Syrjänen, Anne Vainionpää, Raija Reijonen, Tiina Turku,
topic	covid:26f92f95879b65c9db7869f6d862a40e42760ca0#this
Source	Elsevier; Medline; PMC
abstract	Abstract Background: Although known as common causes of upper respiratory infections, rhinoviruses, enteroviruses, and corona-viruses are poorly studied as inducers of wheezing in infants, and their possible role in the development of childhood asthma has not been investigated. Objective: The purposes of this study were to assess the occurrence of RV, enterovirus, and coronavirus infections in wheezing infants and to evaluate the association of these viral findings with early school-age asthma. Methods: In 1999, outcome in relation to asthma was studied in 82 of 100 initially recruited children who had been hospitalized for wheezing in infancy during the period 1992-1993. In 2000, etiologic viral studies regarding the index episode of wheezing were supplemented by rhinovirus, enterovirus, and coronavirus detection by RT-PCR from frozen nasopharyngeal aspirates in 81 of the children for whom adequate samples were available. Of these children, 66 had participated in the follow-up in 1999. Results: Rhinoviruses were identified in 27 (33%) of the 81 children, enteroviruses in 10 (12%), and coronaviruses in none. Rhinoviruses were present as single viral findings in 22 (81%) of the 27 rhinovirus-positive cases, and rhinovirus infections were associated with the presence of atopic dermatitis in infancy. Enteroviruses were commonly encountered in mixed infections and had no association with atopy. As single viral findings, rhinoviruses were associated with the development of asthma (P = .047; odds ratio, 4.14; 95% CI, 1.02-16.77 versus rhinovirus-negative cases [by logistic regression adjusted for age, sex, and atopic dermatitis on entry)]. Conclusion: Our results present rhinoviruses as important inducers of wheezing even in infancy. The association with atopy and subsequent asthma calls for reevaluation of the role of rhinoviruses in the development of asthma. (J Allergy Clin Immunol 2003;111:66-71.)
has issue date	2003-01-31(xsd:dateTime)
bibo:doi	10.1067/mai.2003.33
bibo:pmid	12532098
has license	els-covid
sha1sum (hex)	26f92f95879b65c9db7869f6d862a40e42760ca0
schema:url	https://doi.org/10.1067/mai.2003.33
resource representing a document's title	Rhinovirus-induced wheezing in infancy—the first sign of childhood asthma?
has PubMed Central identifier	PMC7112360
has PubMed identifier	12532098
schema:publication	Journal of Allergy and Clinical Immunology
resource representing a document's body	covid:26f92f95879b65c9db7869f6d862a40e42760ca0#body_text
is http://vocab.deri.ie/void#inDataset of	https://covidontheweb.inria.fr:4443/about/id/http/ns.inria.fr/covid19/26f92f95879b65c9db7869f6d862a40e42760ca0
is schema:about of	named entity 'episode' named entity 'assess' named entity 'COVID-19' named entity '95% CI' named entity 'commonly' named entity 'permissions' named entity 'dermatitis' named entity 'analyses' named entity 'coronavirus' named entity 'wheezing' named entity 'Although' named entity '1992' named entity 'nasopharyngeal' named entity 'IMPORTANT' named entity 'FREE' named entity 'COVID-19' named entity 'AVAILABLE' named entity 'CONCLUSION' named entity 'PRESENT' named entity 'OUR' named entity 'LOGISTIC REGRESSION' named entity 'SAMPLES' named entity 'INITIALLY' named entity 'WHEEZING' named entity 'ORIGINAL SOURCE' named entity 'THEIR' named entity 'POSITIVE' named entity 'ASTHMA' named entity 'VIRAL STUDIES' named entity 'CENTRE' named entity 'ENTEROVIRUSES' named entity 'HOSPITALIZED' named entity 'DETECTION' named entity 'PERMISSIONS' named entity '2000' named entity 'COMMON' named entity 'CAUSES' named entity 'ADJUSTED FOR AGE' named entity '28P' named entity 'SEX' named entity 'ASSESS' named entity 'RELATION' named entity 'FOLLOW-UP' named entity 'VIRAL' named entity 'FUNDED' named entity 'ALLERGY' named entity 'INFECTIONS' named entity 'LONG' named entity 'UPPER RESPIRATORY INFECTIONS' named entity 'FROZEN' named entity '1992' named entity 'FORM' named entity 'THESE' named entity 'OCCURRENCE' named entity 'UNRESTRICTED' named entity 'CLIN' named entity 'BACKGROUND' named entity 'CASES' named entity 'NASOPHARYNGEAL' named entity 'RHINOVIRUS' named entity 'PURPOSES' named entity 'RHINOVIRUSES' named entity 'CORONAVIRUSES' named entity 'SUBSEQUENT' named entity 'ODDS RATIO' named entity 'KNOWN' named entity 'ROLE' named entity '100' named entity 'ACTIVE' named entity 'IMMUNOL' named entity 'FINDINGS' named entity 'DEVELOPMENT' named entity 'RHINITIS'

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