About: Imaging and clinical features of patients with 2019 novel coronavirus SARS-CoV-2

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Imaging and clinical features of patients with 2019 novel coronavirus SARS-CoV-2
Creator	Ding, Yan Gan, Qingxin Guan, Wanhua Hu, Tianli Huang, Deyang Jiang, Rui Jiang, Songfeng Lin, Lin Ling, Zhoukun Liu, Jinxin Luo, Liangping Qu, Jing Tang, Xiaoping Xu, Xi Yu, Chengcheng Zhang, Lieguang Zhang, Zhiping Chen, &
source	Medline; PMC
abstract	BACKGROUND: The pneumonia caused by the 2019 novel coronavirus (SARS-CoV-2, also called 2019-nCoV) recently break out in Wuhan, China, and was named as COVID-19. With the spread of the disease, similar cases have also been confirmed in other regions of China. We aimed to report the imaging and clinical characteristics of these patients infected with SARS-CoV-2 in Guangzhou, China. METHODS: All patients with laboratory-identified SARS-CoV-2 infection by real-time polymerase chain reaction (PCR) were collected between January 23, 2020, and February 4, 2020, in a designated hospital (Guangzhou Eighth People’s Hospital). This analysis included 90 patients (39 men and 51 women; median age, 50 years (age range, 18–86 years). All the included SARS-CoV-2-infected patients underwent non-contrast enhanced chest computed tomography (CT). We analyzed the clinical characteristics of the patients, as well as the distribution characteristics, pattern, morphology, and accompanying manifestations of lung lesions. In addition, after 1–6 days (mean 3.5 days), follow-up chest CT images were evaluated to assess radiological evolution. FINDINGS: The majority of infected patients had a history of exposure in Wuhan or to infected patients and mostly presented with fever and cough. More than half of the patients presented bilateral, multifocal lung lesions, with peripheral distribution, and 53 (59%) patients had more than two lobes involved. Of all included patients, COVID-19 pneumonia presented with ground glass opacities in 65 (72%), consolidation in 12 (13%), crazy paving pattern in 11 (12%), interlobular thickening in 33 (37%), adjacent pleura thickening in 50 (56%), and linear opacities combined in 55 (61%). Pleural effusion, pericardial effusion, and lymphadenopathy were uncommon findings. In addition, baseline chest CT did not show any abnormalities in 21 patients (23%), but 3 patients presented bilateral ground glass opacities on the second CT after 3–4 days. CONCLUSION: SARS-CoV-2 infection can be confirmed based on the patient’s history, clinical manifestations, imaging characteristics, and laboratory tests. Chest CT examination plays an important role in the initial diagnosis of the novel coronavirus pneumonia. Multiple patchy ground glass opacities in bilateral multiple lobular with periphery distribution are typical chest CT imaging features of the COVID-19 pneumonia.
has issue date	2020-02-28(xsd:dateTime)
bibo:doi	10.1007/s00259-020-04735-9
bibo:pmid	32107577
has license	no-cc
sha1sum (hex)	272c530d8b3a2daae3af01fa4a59b350f3a5398b
schema:url	https://doi.org/10.1007/s00259-020-04735-9
resource representing a document's title	Imaging and clinical features of patients with 2019 novel coronavirus SARS-CoV-2
has PubMed Central identifier	PMC7080117
has PubMed identifier	32107577
schema:publication	Eur J Nucl Med Mol Imaging
resource representing a document's body	covid:272c530d8b3a2daae3af01fa4a59b350f3a5398b#body_text
is schema:about of	named entity 'pattern' named entity 'Multiple' named entity '2019' named entity 'lesions' named entity 'median age' named entity 'bilateral' named entity 'Guangzhou' named entity 'lung' named entity 'February 4' named entity 'January 23' named entity 'patients' named entity 'addition' named entity 'SARS-CoV-2' named entity 'evolution' named entity 'thickening' named entity 'China' named entity 'FEVER' named entity 'CHEST COMPUTED TOMOGRAPHY' named entity 'ACCOMPANYING' named entity 'HALF' named entity 'LESIONS' named entity 'BILATERAL' named entity 'CT IMAGING' named entity 'COMBINED' named entity 'BUT' named entity 'MULTIFOCAL' named entity 'CONTRAST' named entity '2859' named entity 'EVOLUTION' named entity 'EXPOSURE' named entity '3-4 DAYS' named entity 'REGIONS' named entity 'EVALUATED' named entity 'DISTRIBUTION' named entity 'ADJACENT' named entity 'LYMPHADENOPATHY' named entity 'China' named entity 'pericardial effusion' named entity 'confirmed' named entity 'baseline' named entity 'peripheral' named entity 'imaging' named entity 'Hospital' named entity 'interlobular' named entity 'Wuhan' named entity 'based' named entity 'enhanced' named entity 'chest' named entity 'People' named entity 'involved' named entity 'PCR' named entity 'Wuhan' named entity 'fever' named entity 'pericardial effusion' named entity 'COVID' named entity 'SARS-CoV-2' named entity 'COVID-19' named entity 'China' named entity 'PCR' named entity 'chest CT' named entity 'China' named entity 'morphology' named entity 'evolution' named entity 'SARS-CoV-2'

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