About: Oral Immunization of Chickens With Recombinant Lactobacillus plantarum Vaccine Against Early ALV-J Infection

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Oral Immunization of Chickens With Recombinant Lactobacillus plantarum Vaccine Against Early ALV-J Infection Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Oral Immunization of Chickens With Recombinant Lactobacillus plantarum Vaccine Against Early ALV-J Infection
Creator	Liu, Liu Wang, Hongwei Liu, Jianzhu Geng, Na Liu, Kangping Liu, Yongxia Qu, Yi Shi, Mengke Wang, Shenghua Xu, Yuliang Zhou, Dong Gershwin, Laurel Qu, Zhou Xu, Shi
Source	PMC
abstract	In this study, a novel oral vaccine of recombinant Lactobacillus plantarum (L. plantarum) containing the gp85 protein was explored, and the effects of this vaccine on the prevention of subgroup J Avian Leukosis Virus (ALV-J) infection were assessed. In the current study, the gp85 protein of ALV-J was expressed on the surface of L. plantarum with the surface-display motif, pgsA, by constructing a shuttle vector pMG36e:pgsA:gp85. Surface localization of the fusion protein was verified by western blotting and flow cytometry. Subsequently, Specific Pathogen Free Hy-Line Brown layer chickens were orally vaccinated with the recombinant L. plantarum and presented with high levels of serum immunoglobulin G (IgG) and secretory immunoglobulin A (sIgA) titers in bile and duodenal-mucosal fluid. After challenged with ALV-J of a 3 × 10(3) 50% tissue culture infective dose (TCID50), serum samples of the chickens were collected and viremia was analyzed. Results showed that, compared to the L. plantarum and PBS control group, the recombinant L. plantarum group showed a significant rise in antibody levels after inoculation, and provide improved protection against ALV-J according to viremia detection. These results indicate that oral immunization with the recombinant L. plantarum provided an effective means for eliciting protective immune response against early ALV-J infection.
has issue date	2019-10-02(xsd:dateTime)
bibo:doi	10.3389/fimmu.2019.02299
bibo:pmid	31632395
has license	cc-by
sha1sum (hex)	2835b0f9f06e3e829cfa7d3f1e3805af94249d65
schema:url	https://doi.org/10.3389/fimmu.2019.02299
resource representing a document's title	Oral Immunization of Chickens With Recombinant Lactobacillus plantarum Vaccine Against Early ALV-J Infection
has PubMed Central identifier	PMC6783503
has PubMed identifier	31632395
schema:publication	Front Immunol
resource representing a document's body	covid:2835b0f9f06e3e829cfa7d3f1e3805af94249d65#body_text
is schema:about of	named entity 'viremia' named entity 'These' named entity 'Virus' named entity 'recombinant' named entity 'antibody' named entity 'presented' named entity 'Vaccine' named entity 'With' named entity 'ACCORDING' named entity 'GROUP' named entity 'PREVENTION OF' named entity 'HIGH' named entity 'SHUTTLE VECTOR' named entity 'WESTERN BLOTTING' named entity 'LAYER' named entity 'DISPLAY' named entity 'COLLECTED' named entity 'RISE' named entity 'PROVIDE' named entity 'CONSTRUCTING' named entity 'THESE' named entity 'EFFECTS' named entity 'LEVELS' named entity 'ELICITING' named entity 'ORAL IMMUNIZATION' named entity 'CHICKENS' named entity 'TISSUE CULTURE' named entity 'SUBGROUP' named entity 'COMPARED' named entity 'MUCOSAL' named entity 'FUSION PROTEIN' named entity 'SERUM' named entity 'VERIFIED' named entity 'CURRENT' named entity 'EARLY' named entity 'VACCINE' named entity 'ANTIBODY' named entity 'ORAL VACCINE' named entity 'FREE' named entity 'DETECTION' named entity 'VACCINATED' named entity 'MOTIF' named entity 'INOCULATION' named entity 'IMMUNE RESPONSE' named entity 'PROTEIN ' named entity 'RECOMBINANT' named entity '50%' named entity 'INFECTIVE DOSE' named entity 'CONTAINING' named entity 'EFFECTIVE' named entity 'SERUM IMMUNOGLOBULIN G' named entity 'ORAL IMMUNIZATION' named entity 'PRESENTED' named entity 'IMPROVED' named entity 'NOVEL' named entity 'VIREMIA' named entity 'SECRETORY IMMUNOGLOBULIN A' named entity 'LINE' named entity 'SAMPLES' named entity 'STUDY' named entity 'MEANS' named entity 'LOCALIZATION' named entity 'RECOMBINANT' named entity 'INFECTION' named entity 'VACCINE' named entity 'FLUID' named entity 'ORALLY' named entity 'LACTOBACILLUS PLANTARUM'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software