About: Association between chest CT features and clinical course of Coronavirus Disease 2019

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Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Association between chest CT features and clinical course of Coronavirus Disease 2019
Creator	Liu, Ping Wang, Na Li, Qiang Guo, Qian Luo, Zhibing Tang, Yuling Wang, Feilong Ran, Linyu
Source	Elsevier; Medline; PMC
abstract	PURPOSE: This retrospective study aims to illustrate the radiographic characteristics of Coronavirus Disease 2019 and the correlation with the clinical course. METHODS: 195 hospitalized patients confirmed as Coronavirus Disease 2019 at First Hospital of Changsha, Hunan Province from December 31, 2019 to February 20, 2020 were enrolled. Chest computed tomography scan, clinical data and laboratory tests results were collected accordingly. Variable characteristics were recorded, radiographic evolution and outcome were analyzed along with the time course. Representative laboratory tests results were analyzed based on the image findings. RESULTS: Majority of the patients showed bilateral (73.8%), multiple lobes involvements (75.9%), peripheral distribution (83.1%), ground-glass opacification (41.0%), increased vascular margins (63.1%), long axis parallelism (55.9%), patchy ground-glass opacities beneath the pleura (51.3%) and consolidation (45.6%). According to the repeated radiology analysis, patients of improving/stable group tended to have younger age compared with worsening group (45.3 ± 15.0 VS. 59.3 ± 13.5, P = 0.001). Based on the laboratory test results, patients with positive image findings shared elder age, 46.0 (35.0–60.0)VS.31.0 (12.0–37.0) P < 0.001, and higher chance developing fever(P < 0.05); higher level of lymphocytes, C-reactive protein, erythrocyte sedimentation rate and lactate dehydrogenase; lower level of white blood cells, neutrophil and albumin(P < 0.001). CONCLUSIONS: There are several specific image changes along with the disease progression may be helpful in early recognition and differential diagnosis of Coronavirus Disease 2019. Comprehensive assessments of both imaging feature and laboratory test results may offer an intact knowledge of Coronavirus Disease 2019.
has issue date	2020-04-22(xsd:dateTime)
bibo:doi	10.1016/j.rmed.2020.105989
bibo:pmid	32364962
has license	no-cc
sha1sum (hex)	2ba064bec028d3d9fad7afc8e740cb2054aa1d9a
schema:url	https://doi.org/10.1016/j.rmed.2020.105989
resource representing a document's title	Association between chest CT features and clinical course of Coronavirus Disease 2019
has PubMed Central identifier	PMC7175878
has PubMed identifier	32364962
schema:publication	Respir Med
resource representing a document's body	covid:2ba064bec028d3d9fad7afc8e740cb2054aa1d9a#body_text
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