About: Description and initial characterization of metatranscriptomic nidovirus-like genomes from the proposed new family Abyssoviridae, and from a sister group to the Coronavirinae, the proposed genus Alphaletovirus

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About: Description and initial characterization of metatranscriptomic nidovirus-like genomes from the proposed new family Abyssoviridae, and from a sister group to the Coronavirinae, the proposed genus Alphaletovirus Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Description and initial characterization of metatranscriptomic nidovirus-like genomes from the proposed new family Abyssoviridae, and from a sister group to the Coronavirinae, the proposed genus Alphaletovirus
Creator	Gulyaeva, Anastasia Neuman, Benjamin Bukhari, Khulud Jiang, Jianping Mulley, Geraldine Shu, Guocheng Zhao, Lanying
topic	covid:2c49c91243848a43c9f2f6610fa237e3f0aaf339#this
Source	Elsevier; Medline; PMC
abstract	Abstract Transcriptomics has the potential to discover new RNA virus genomes by sequencing total intracellular RNA pools. In this study, we have searched publicly available transcriptomes for sequences similar to viruses of the Nidovirales order. We report two potential nidovirus genomes, a highly divergent 35.9 kb likely complete genome from the California sea hare Aplysia californica, which we assign to a nidovirus named Aplysia abyssovirus 1 (AAbV), and a coronavirus-like 22.3 kb partial genome from the ornamented pygmy frog Microhyla fissipes, which we assign to a nidovirus named Microhyla alphaletovirus 1 (MLeV). AAbV was shown to encode a functional main proteinase, and a translational readthrough signal. Phylogenetic analysis suggested that AAbV represents a new family, proposed here as Abyssoviridae. MLeV represents a sister group to the other known coronaviruses. The importance of MLeV and AAbV for understanding nidovirus evolution, and the origin of terrestrial nidoviruses are discussed.
has issue date	2018-11-30(xsd:dateTime)
bibo:doi	10.1016/j.virol.2018.08.010
bibo:pmid	30199753
has license	els-covid
sha1sum (hex)	2c49c91243848a43c9f2f6610fa237e3f0aaf339
schema:url	https://doi.org/10.1016/j.virol.2018.08.010
resource representing a document's title	Description and initial characterization of metatranscriptomic nidovirus-like genomes from the proposed new family Abyssoviridae, and from a sister group to the Coronavirinae, the proposed genus Alphaletovirus
has PubMed Central identifier	PMC7112036
has PubMed identifier	30199753
schema:publication	Virology
resource representing a document's body	covid:2c49c91243848a43c9f2f6610fa237e3f0aaf339#body_text
is http://vocab.deri.ie/void#inDataset of	https://covidontheweb.inria.fr:4443/about/id/http/ns.inria.fr/covid19/2c49c91243848a43c9f2f6610fa237e3f0aaf339
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