About: The utility of delta neutrophil index in differentiation of pulmonary tuberculosis from community acquired pneumonia

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About: The utility of delta neutrophil index in differentiation of pulmonary tuberculosis from community acquired pneumonia Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	The utility of delta neutrophil index in differentiation of pulmonary tuberculosis from community acquired pneumonia
Creator	Kim, Dong-Gyu Rim, Tae Sim, Yun Woo, Byung
Source	Medline; PMC
abstract	No data exist on the usefulness of the delta neutrophil index (DNI) to discriminate pulmonary tuberculosis (PTB) from community-acquired pneumonia (CAP). We performed a retrospective cohort study involving patients with PTB (n = 62) and CAP (n = 215), and compared their initial DNI levels. The median DNI values were 0% (interquartile ranges [IQR] 0–0.2%) and 1.6% (IQR 0.7–2.9%) in PTB and CAP, respectively, which was significantly lower in PTB patients (P < 0.001). Sixty-nine percent of patients with PTB had DNI value of 0%; however, only 15% of patients with CAP had 0% DNI. The discriminatory power of the DNI for diagnosing PTB was high with 89% sensitivity and 67% specificity at a DNI cut-off ≤ 1.0% (area under the curve, 0.852). The diagnostic sensitivity and negative predictive value (NPV) for PTB were 89% (55/62) and 95% (145/152) at the DNI cut-off ≤ 1.0%, respectively, and in multivariate analyses after adjusting for other factors (smoking, no fever, upper lobe involvement), DNI ≤ 1.0% remained significant (odds ratio, 15.265; P < 0.001). We demonstrated that the DNI was lower in PTB compared with CAP, and an initially elevated DNI (>1.0%) may be useful to rule out the possibility of PTB due to its high NPV.
has issue date	2018-08-17(xsd:dateTime)
bibo:doi	10.1038/s41598-018-30967-9
bibo:pmid	30120386
has license	cc-by
sha1sum (hex)	2c5f5500b79b97672aca47a26df7996390c30459
schema:url	https://doi.org/10.1038/s41598-018-30967-9
resource representing a document's title	The utility of delta neutrophil index in differentiation of pulmonary tuberculosis from community acquired pneumonia
has PubMed Central identifier	PMC6098156
has PubMed identifier	30120386
schema:publication	Sci Rep
resource representing a document's body	covid:2c5f5500b79b97672aca47a26df7996390c30459#body_text
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