About: Do Viruses Exchange Genes across Superkingdoms of Life?

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Do Viruses Exchange Genes across Superkingdoms of Life? Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Do Viruses Exchange Genes across Superkingdoms of Life?
Creator	Caetano-Anollés, Gustavo Nasir, Arshan Paez-Espino, David Kim, Kyung Malik, Shahana Allers, Thorsten Azem-E-Zahra, Syeda Bernick, David
source	Medline; PMC
abstract	Viruses can be classified into archaeoviruses, bacterioviruses, and eukaryoviruses according to the taxonomy of the infected host. The host-constrained perception of viruses implies preference of genetic exchange between viruses and cellular organisms of their host superkingdoms and viral origins from host cells either via escape or reduction. However, viruses frequently establish non-lytic interactions with organisms and endogenize into the genomes of bacterial endosymbionts that reside in eukaryotic cells. Such interactions create opportunities for genetic exchange between viruses and organisms of non-host superkingdoms. Here, we take an atypical approach to revisit virus-cell interactions by first identifying protein fold structures in the proteomes of archaeoviruses, bacterioviruses, and eukaryoviruses and second by tracing their spread in the proteomes of superkingdoms Archaea, Bacteria, and Eukarya. The exercise quantified protein structural homologies between viruses and organisms of their host and non-host superkingdoms and revealed likely candidates for virus-to-cell and cell-to-virus gene transfers. Unexpected lifestyle-driven genetic affiliations between bacterioviruses and Eukarya and eukaryoviruses and Bacteria were also predicted in addition to a large cohort of protein folds that were universally shared by viral and cellular proteomes and virus-specific protein folds not detected in cellular proteomes. These protein folds provide unique insights into viral origins and evolution that are generally difficult to recover with traditional sequence alignment-dependent evolutionary analyses owing to the fast mutation rates of viral gene sequences.
has issue date	2017-10-31(xsd:dateTime)
bibo:doi	10.3389/fmicb.2017.02110
bibo:pmid	29163404
has license	cc-by
sha1sum (hex)	2c9a3072e8533ac8c5a74abfc595966d516a7878
schema:url	https://doi.org/10.3389/fmicb.2017.02110
resource representing a document's title	Do Viruses Exchange Genes across Superkingdoms of Life?
has PubMed Central identifier	PMC5671483
has PubMed identifier	29163404
schema:publication	Front Microbiol
resource representing a document's body	covid:2c9a3072e8533ac8c5a74abfc595966d516a7878#body_text
is schema:about of	named entity 'VIRAL GENE' named entity 'AFFILIATIONS' named entity 'LYTIC' named entity 'REDUCTION' named entity 'HOST' named entity 'HOST CELLS' named entity 'UNEXPECTED' named entity 'THEIR' named entity 'EITHER' named entity 'NOT DETECTED' named entity 'VIRUS' named entity 'BACTERIAL' named entity 'PERCEPTION' named entity 'SPREAD' named entity 'FREQUENTLY' named entity 'VIRAL' named entity 'ESTABLISH' named entity 'RESIDE' named entity 'GENOMES' named entity 'ATYPICAL' named entity 'GENERALLY' named entity 'PROTEIN FOLD' named entity 'APPROACH' named entity 'CELL' named entity 'REVEALED' named entity 'DIFFICULT' named entity 'ARCHAEA' named entity 'PROTEOMES' named entity 'VIRUSES' named entity 'HERE' named entity 'UNIQUE' named entity 'CREATE' named entity 'ACROSS' named entity 'LARGE' named entity 'GENETIC' named entity 'THESE' named entity 'SPECIFIC PROTEIN' named entity 'CONSTRAINED' named entity 'LIFESTYLE' named entity 'TRADITIONAL' named entity 'TRANSFERS' named entity 'VIRAL AND' named entity 'MUTATION RATES' named entity 'EXCHANGE' named entity 'VIRUSES' named entity 'GENES' named entity 'LIFE' named entity 'SEQUENCE ALIGNMENT' named entity 'ACCORDING' named entity 'CLASSIFIED' named entity 'RECOVER' named entity 'DEPENDENT' named entity 'ORGANISMS' named entity 'IDENTIFYING' named entity 'PROVIDE' named entity 'LIKELY' named entity 'STRUCTURES' named entity 'GENETIC EXCHANGE' named entity 'PROTEIN ' named entity 'PROTEIN FOLDS' named entity 'FAST' named entity 'EUKARYA' named entity 'SEQUENCES' named entity 'DRIVEN' named entity 'SECOND' named entity 'CELLULAR ORGANISMS' named entity 'SHARED' named entity 'NON-' named entity 'BACTERIA' named entity 'STRUCTURAL' named entity 'COHORT' named entity 'GENE' named entity 'INTERACTIONS' named entity 'ORIGINS'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2025 OpenLink Software