About: Recent advances in understanding Crimean–Congo hemorrhagic fever virus

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Recent advances in understanding Crimean–Congo hemorrhagic fever virus
Creator	Feldmann, Heinz Hawman, David
Source	Medline; PMC
abstract	Crimean-Congo hemorrhagic fever virus (CCHFV) is a widely distributed hemorrhagic fever virus and the cause of hemorrhagic disease in Africa, Southern and Eastern Europe, the Middle East, India and Asia. Recent emergence of CCHFV into Spain indicates that the geographic range of this virus is expanding and the presence of its tick vector in several countries without reported disease suggest that CCHFV will continue to spread. Research into CCHFV was historically limited by a lack of suitable animal models and tools to study viral pathogenesis. However, in the past few years the toolset for studying CCHFV has expanded with small animal and non-human primate models for CCHFV being developed along with a reverse genetics system that allows for investigation of viral determinants of disease. These tools have been utilized to understand how CCHFV antagonizes host restriction factors and to develop novel vaccine candidates that may help limit the substantial morbidity and mortality in humans caused by CCHFV.
has issue date	2018-10-29(xsd:dateTime)
bibo:doi	10.12688/f1000research.16189.1
bibo:pmid	30416710
has license	cc-by
sha1sum (hex)	2e7a5d9a03e6fdbce778e489686a2533d47f7463
schema:url	https://doi.org/10.12688/f1000research.16189.1
resource representing a document's title	Recent advances in understanding Crimean–Congo hemorrhagic fever virus
has PubMed Central identifier	PMC6206615
has PubMed identifier	30416710
schema:publication	F1000Res
resource representing a document's body	covid:2e7a5d9a03e6fdbce778e489686a2533d47f7463#body_text
is schema:about of	named entity 'Asia' named entity 'RECENT' named entity 'ANIMAL MODELS ' named entity 'VIRUS' named entity 'HOST' named entity 'SYSTEM' named entity 'IN THE PAST' named entity 'TICK' named entity 'COUNTRIES' named entity 'VIRAL PATHOGENESIS' named entity 'PRESENCE OF' named entity 'SOUTHERN' named entity 'YEARS' named entity 'CONTINUE' named entity 'EXPANDING' named entity 'CRIMEAN-CONGO HEMORRHAGIC FEVER VIRUS' named entity 'HOW' named entity 'EXPANDED ' named entity 'ALLOWS' named entity 'HAVE' named entity 'AFRICA' named entity 'THESE' named entity 'SPREAD' named entity 'UNDERSTAND' named entity 'DISEASE' named entity 'CAUSE' named entity 'REPORTED' named entity 'SPAIN' named entity 'REVERSE GENETICS' named entity 'LIMIT' named entity 'INDIA' named entity 'ITS' named entity 'VIRAL' named entity 'VACCINE' named entity 'APPROVED' named entity 'CRIMEAN-CONGO HEMORRHAGIC FEVER VIRUS' named entity 'VECTOR' named entity 'HEMORRHAGIC FEVER VIRUS' named entity 'RESEARCH' named entity 'RECENT' named entity 'DETERMINANTS' named entity 'SUGGEST' named entity 'MODELS' named entity 'UNDERSTANDING' named entity 'SUITABLE' named entity 'MORBIDITY AND MORTALITY' named entity 'HELP' named entity 'DISTRIBUTED' named entity 'IS A' named entity 'LACK' named entity 'INVESTIGATION' named entity 'SMALL ANIMAL' named entity 'ASIA' named entity 'RESTRICTION' named entity 'NON-HUMAN PRIMATE' named entity 'GEOGRAPHIC RANGE' named entity 'LIMITED BY' named entity 'STUDY' named entity 'NOVEL' named entity 'HEMORRHAGIC DISEASE' named entity 'EMERGENCE' named entity 'TOOLS' named entity 'EASTERN EUROPE' named entity 'MIDDLE EAST' named entity 'HUMANS' named entity 'BEING' named entity 'virus' named entity 'Southern' named entity 'studying' named entity 'primate' named entity 'hemorrhagic' named entity 'Africa' named entity 'geographic' named entity 'emergence' named entity 'antagonizes' named entity 'morbidity' named entity 'hemorrhagic fever virus' named entity 'Spain' named entity 'small animal' named entity 'CCHFV'

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