About: Antimicrobial resistance in southern China: results of prospective surveillance in Dongguan city, 2017()

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Antimicrobial resistance in southern China: results of prospective surveillance in Dongguan city, 2017()
Creator	Metsini, Aliki Zhou, M Wang, Jiancong Zhou, Mouqing Pittet, D Zingg, Walter Wang, J Guo, Z Huang, G Huang, Guobin Metsini, A Sauser, Guo Sauser, J Sauser, Julien Zingg, W
source	Elsevier; Medline; PMC
abstract	BACKGROUND: Few studies have estimated the burden of infections due to antimicrobial-resistant (AMR) pathogens in China. AIM: To summarize antimicrobial resistance and assess the frequency of community-associated infections (CAIs) and healthcare-associated infections (HCAIs) due to AMR pathogens in Dongguan city, China. METHODS: Seven acute care hospitals provided antimicrobial susceptibility data for 2017, from which ‘bug–drug’ combinations were analysed. To calculate incidence proportions of CAI and incidence densities of HCAI, data from three tertiary care hospitals were merged with patient data, obtained from the Dongguan Nosocomial Infection Surveillance System. FINDINGS: A total of 16,548 pathogens were analysed. Non-susceptibility to third-generation cephalosporins (3GCs) in Escherichia coli and Klebsiella pneumoniae was 43.9% and 30.2%, respectively. Non-susceptibility to carbapenems in Pseudomonas aeruginosa and Acinetobacter baumannii was 29.5% and 50.9%, respectively. A quarter of Staphylococcus aureus (26.3%) were non-susceptible to oxacillin. The incidence density of HCAI due to E. coli non-susceptible to 3GCs and fluoroquinolones combined was 0.09 (95% confidence interval: 0.07–0.11) per 1000 patient-days. Both E. coli and K. pneumoniae were the predominant pathogens isolated from blood. Compared with the 2017 European Antimicrobial Resistance Surveillance Network report, the incidence proportion of bloodstream infections due to multidrug-resistant E. coli was significantly higher (14.9% and 4.6%, respectively). CONCLUSION: The incidence of non-susceptible bug–drug combinations in Dongguan city was lower compared with China as a whole. Non-susceptible bug–drug combinations were significantly more frequent in HCAI compared with CAI. The incidence proportion of bloodstream infections due to multidrug-resistant pathogens in Dongguan City was higher compared with Europe.
has issue date	2020-03-31(xsd:dateTime)
bibo:doi	10.1016/j.jhin.2020.03.029
bibo:pmid	32243952
has license	no-cc
sha1sum (hex)	2e8b59bec949d262c1212fb779206da1fd09d88f
schema:url	https://doi.org/10.1016/j.jhin.2020.03.029
resource representing a document's title	Antimicrobial resistance in southern China: results of prospective surveillance in Dongguan city, 2017()
has PubMed Central identifier	PMC7270154
has PubMed identifier	32243952
schema:publication	J Hosp Infect
resource representing a document's body	covid:2e8b59bec949d262c1212fb779206da1fd09d88f#body_text
is schema:about of	named entity 'RESULTS' named entity 'Antimicrobial resistance' named entity 'surveillance' named entity '2017' named entity 'CITY' named entity 'PROOF' named entity 'JOURNAL ' named entity 'PRE' named entity 'CHINA' named entity 'PROSPECTIVE' named entity 'SURVEILLANCE' named entity 'ANTIMICROBIAL RESISTANCE' named entity 'SOUTHERN' named entity 'pathogens' named entity 'point prevalence' named entity 'pathogens' named entity 'Dongguan' named entity 'southern China' named entity 'Southern China' named entity 'pathogens' named entity 'Staphylococcus aureus' named entity 'Asia' named entity 'fluoroquinolones' named entity 'K. pneumoniae' named entity 'pathogens' named entity 'E. coli' named entity 'K. pneumoniae' named entity 'Europe' named entity 'P. aeruginosa' named entity 'carbapenems' named entity 'E. coli' named entity 'France' named entity 'Guangdong' named entity 'pathogens' named entity 'K. pneumoniae' named entity 'pathogens' named entity 'fluoroquinolones' named entity 'K. pneumoniae' named entity 'A. baumannii' named entity 'E. coli' named entity 'CRAB' named entity 'carbapenems' named entity 'K. pneumoniae' named entity 'fluoroquinolones' named entity 'antimicrobial' named entity 'tertiary-care' named entity '95% CI' named entity 'CHINET' named entity 'E. coli' named entity 'Germany' named entity 'China' named entity 'Mainland China' named entity '5.1' named entity 'European Centre for Disease Prevention and Control' named entity 'Enterococcus faecium' named entity 'bloodstream infections' named entity 'Southern China' named entity 'severe acute respiratory syndrome' named entity 'infection prevention and control' named entity 'tertiary-care' named entity 'infectious diseases' named entity 'Enterobacteriaceae' named entity 'Third-generation cephalosporin' named entity 'Dongguan' named entity 'P. aeruginosa' named entity 'WHO' named entity 'Asian'

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