About: An in vitro study of theaflavins extracted from black tea to neutralize bovine rotavirus and bovine coronavirus infections

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About: An in vitro study of theaflavins extracted from black tea to neutralize bovine rotavirus and bovine coronavirus infections Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	An in vitro study of theaflavins extracted from black tea to neutralize bovine rotavirus and bovine coronavirus infections
Creator	Clark, K Grant, P Phillips, T Sarr, A Woode, G Belakere, J Swaggerty, C
Source	Elsevier; Medline; PMC
abstract	Crude theaflavin was extracted from black tea and then fractionated by HPLC into five components (initial peaks (IP), TF(1), TF(2A), TF(2B), and TF(3)). The crude extract and the various fractions of theaflavin were collected and tested, individually and in combination, for antirotaviral activity. The mean effective concentration (EC(50)) was calculated and compared. Activity varied from the most active being the uncharacterized theaflavin-like initial peaks (IP) with an EC(50) of 0.125 μg/ml to the least active being theaflavin-3 monogallate (TF(2A)) with an EC(50) of 251.39 μg/ml. The combination of TF(1)+TF(2A)+TF(2B)+TF(3) was more active than the sum of the activities of these four fractions individually, indicating synergism among the peaks. Only the crude extract was assayed for activity against coronavirus; the EC(50) was 34.7 μg/ml.
has issue date	1998-10-01(xsd:dateTime)
bibo:doi	10.1016/s0378-1135(98)00242-9
bibo:pmid	9850995
has license	no-cc
sha1sum (hex)	2e98e30e0e5ffd1f8475255eaa2cee8891bd4ee5
schema:url	https://doi.org/10.1016/s0378-1135%2898%2900242-9
resource representing a document's title	An in vitro study of theaflavins extracted from black tea to neutralize bovine rotavirus and bovine coronavirus infections
has PubMed Central identifier	PMC7117136
has PubMed identifier	9850995
schema:publication	Vet Microbiol
resource representing a document's body	covid:2e98e30e0e5ffd1f8475255eaa2cee8891bd4ee5#body_text
is schema:about of	named entity 'COMBINATION' named entity '0.125' named entity 'INITIAL' named entity 'ACTIVITY' named entity 'COLLECTED' named entity 'COMPARED' named entity 'MG%' named entity 'TESTED' named entity 'MEAN' named entity 'LIKE' named entity 'EXTRACTED' named entity 'HPLC' named entity 'INDICATING' named entity 'BLACK TEA' named entity 'SUM' named entity 'FRACTIONS OF' named entity 'FRACTIONS' named entity 'THESE' named entity 'PEAKS' named entity 'ACTIVE' named entity 'CORONAVIRUS' named entity 'BEING' named entity '251' named entity 'EFFECTIVE' named entity 'SYNERGISM' named entity 'THEAFLAVIN' named entity 'ACTIVITIES' named entity 'CALCULATED' named entity 'COMPONENTS' named entity 'VARIOUS' named entity 'FRACTIONATED' named entity 'CONCENTRATION' named entity 'EXTRACT' covid:arg/2e98e30e0e5ffd1f8475255eaa2cee8891bd4ee5 named entity 'theaflavin' named entity 'tested' named entity 'Activity' named entity 'effective concentration' named entity 'peaks' named entity 'theaflavin' named entity 'theaflavin' named entity 'HPLC' named entity 'centrifuged' named entity 'wavelength' named entity 'MDL Information Systems' named entity 'tea' named entity 'black tea' named entity 'conformation' named entity 'fractionation' named entity 'tea leaves' named entity 'vaccines' named entity 'adsorbent' named entity 'immunofluorescent' named entity 'influenza' named entity 'Theaflavin' named entity 'bovine' named entity 'centrifuged' named entity 'coxsackie virus' named entity 'rotavirus' named entity 'bovine' named entity 'antisera' named entity 'HBP' named entity 'LA50' named entity 'food additives' named entity 'high performance liquid chromatography' named entity 'adsorbing' named entity 'precipitate' named entity 'ethyl acetate' named entity 'charcoal' named entity 'rotavirus' named entity 'viruses' named entity 'HPLC' named entity 'bovine' named entity 'tea' named entity 'Microtiter plate'

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