About: COVID-19 and newborn health: systematic review

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	COVID-19 and newborn health: systematic review
Creator	Jaenisch, Thomas Berman, Stephen De Mucio, Bremen Duran, Pablo Forster, Thais Gomez Ponce De Leon, Rodolfo Niermeyer, Susan Serruya, Suzanne
Source	Medline; PMC
abstract	OBJECTIVE. To describe perinatal and neonatal outcomes in newborns exposed to SARS-CoV-2. METHODS. A systematic review was conducted by searching PubMed Central, LILACS, and Google Scholar using the keywords ‘covid ’ AND ‘newborn’ OR ‘child’ OR ‘infant,’ on 18 March 2020, and again on 17 April 2020. One researcher conducted the search and extracted data on demographics, maternal outcomes, diagnostic tests, imaging, and neonatal outcomes. RESULTS. Of 256 publications identified, 20 met inclusion criteria and comprised neonatal outcome data for 222 newborns whose mothers were suspected or confirmed to be SARS-CoV-2 positive perinatally (17 studies) or of newborns referred to hospital with infection/pneumonia (3 studies). Most (12 studies) were case-series reports; all were from China, except three (Australia, Iran, and Spain). Of the 222 newborns, 13 were reported as positive for SARS-CoV-2; most of the studies reported no or mild symptoms and no adverse perinatal outcomes. Two papers among those from newborns who tested positive reported moderate or severe clinical characteristics. Five studies using data on umbilical cord blood, placenta, and/or amniotic fluid reported no positive results. Nine studies reported radiographic imaging, including 5 with images of pneumonia, increased lung marking, thickened texture, or high-density nodular shadow. Minor, non-specific changes in biochemical variables were reported. Studies that tested breast milk reported negative SARS-CoV-2 results. CONCLUSIONS. Given the paucity of studies at this time, vertical transmission cannot be confirmed or denied. Current literature does not support abstaining from breastfeeding nor separating mothers and newborns. Further evidence and data collection networks, particularly in the Americas, are needed for establishing definitive guidelines and recommendations.
has issue date	2020-04-27(xsd:dateTime)
bibo:doi	10.26633/rpsp.2020.54
bibo:pmid	32454807
has license	cc-by-nc-nd
sha1sum (hex)	2ea7ebfb7fdbb41475733d8c6b6a25e04f875f79
schema:url	https://doi.org/10.26633/rpsp.2020.54
resource representing a document's title	COVID-19 and newborn health: systematic review
has PubMed Central identifier	PMC7241573
has PubMed identifier	32454807
schema:publication	Rev Panam Salud Publica
resource representing a document's body	covid:2ea7ebfb7fdbb41475733d8c6b6a25e04f875f79#body_text
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