About: Acute respiratory infections in hospitalized children in Vientiane, Lao PDR – the importance of Respiratory Syncytial Virus

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About: Acute respiratory infections in hospitalized children in Vientiane, Lao PDR – the importance of Respiratory Syncytial Virus Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Acute respiratory infections in hospitalized children in Vientiane, Lao PDR – the importance of Respiratory Syncytial Virus
Creator	Richet, Hervé De Lamballerie, Xavier Dubot-Pérès, Audrey Lai, Jana Lim, Ruth Mayxay, Mayfong Morpeth, Melinda Phommachan, Souphatsone Syladeth, Chanthaphone Vilivong, Keoudomphone Newton, Paul Dance, David Nguyen, Van Russell, Fiona
Source	Medline; PMC
abstract	The Human respiratory syncytial virus (RSV) is one of the most important viral pathogens, causing epidemics of acute respiratory infection (ARI), especially bronchiolitis and pneumonia, in children worldwide. To investigate the RSV burden in Laos, we conducted a one-year study in children <5 years old admitted to Mahosot Hospital, Vientiane Capital, to describe clinical and epidemiological characteristics and predictive factors for severity of RSV-associated ARI. Pooled nasal and throat swabs were tested using multiplex real-time PCR for 33 respiratory pathogens (FTD(®) kit). A total of 383 patients were included, 277 (72.3%) of whom presented with pneumonia. 377 (98.4%) patients were positive for at least one microorganism, of which RSV was the most common virus (41.0%), with a peak observed between June and September, corresponding to the rainy season. Most RSV inpatients had pneumonia (84.1%), of whom 35% had severe pneumonia. Children <3-months old were a high-risk group for severe pneumonia, independently of RSV infection. Our study suggests that RSV infection is frequent in Laos and commonly associated with pneumonia in hospitalized young children. Further investigations are required to provide a better overall view of the Lao nationwide epidemiology and public health burden of RSV infection over time.
has issue date	2017-08-24(xsd:dateTime)
bibo:doi	10.1038/s41598-017-09006-6
bibo:pmid	28839157
has license	cc-by
sha1sum (hex)	2f2f4654524b26b1b253d2ca5a6f6bf7e7455f36
schema:url	https://doi.org/10.1038/s41598-017-09006-6
resource representing a document's title	Acute respiratory infections in hospitalized children in Vientiane, Lao PDR – the importance of Respiratory Syncytial Virus
has PubMed Central identifier	PMC5571090
has PubMed identifier	28839157
schema:publication	Sci Rep
resource representing a document's body	covid:2f2f4654524b26b1b253d2ca5a6f6bf7e7455f36#body_text
is schema:about of	named entity 'time' named entity 'virus' named entity 'Vientiane' named entity 'MICROORGANISM' named entity 'SEPTEMBER' named entity 'MULTIPLEX REAL-TIME PCR' named entity 'FREQUENT' named entity 'PATIENTS' named entity 'RAINY SEASON' named entity 'INPATIENTS' named entity 'RSV' named entity 'REAL-TIME PCR ' named entity 'KIT' named entity 'HOSPITALIZED' named entity 'PEAK' named entity '2872' named entity 'RSV INFECTION' named entity 'JUNE' named entity 'LAOS' named entity 'POSITIVE FOR' named entity 'STUDY' named entity 'LAO' named entity '2884' named entity 'PUBLIC HEALTH' named entity 'BETTER' named entity 'HOSPITALIZED CHILDREN' named entity 'ACUTE RESPIRATORY INFECTIONS' named entity 'RESPIRATORY PATHOGENS' named entity 'HIGH-RISK GROUP' named entity 'RESPIRATORY SYNCYTIAL VIRUS' named entity 'YOUNG CHILDREN' named entity 'VIRUS' named entity 'LAO' named entity 'PDR' named entity 'TOTAL' named entity 'REQUIRED' named entity 'PRESENTED' named entity 'MONTHS OLD' named entity 'ASSOCIATED WITH' named entity '277' named entity 'TIME' named entity 'INCLUDED' named entity 'TO PROVIDE' named entity 'CHILDREN' named entity 'PNEUMONIA' named entity 'TESTED' named entity 'SEVERE PNEUMONIA' named entity 'OUR' named entity 'INVESTIGATIONS' named entity 'OBSERVED' named entity 'BURDEN' named entity 'USING' named entity 'VIEW' named entity 'EPIDEMIOLOGY' named entity 'COMMON' named entity 'OVERALL' named entity 'patients' named entity 'pathogens' named entity 'burden' named entity 'study' named entity 'pneumonia' named entity 'independently' named entity 'September' named entity 'pneumonia' named entity 'real-time PCR' named entity 'pneumonia' named entity 'Lao PDR' named entity 'vomiting'

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