About: A snapshot of the Covid-19 pandemic among pregnant women in France

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	A snapshot of the Covid-19 pandemic among pregnant women in France
Creator	Deruelle, Philippe Morel, Olivier Picone, Olivier Sentilhes, Loïc Alessandrini, Vivien Azria, Elie Blanc, Julie Bohec, Caroline Bornes, Marie Bretelle, Florence Ceccaldi, Pierre-François Chalet, Yasmine Chauleur, Céline Cordier, Anne-Gael Desbrière, Raoul Doret, Muriel Dreyfus, Michel Driessen, Marine Fermaut, Marion Gallot, Denis Garabédian, Charles Huissoud, Cyril Kayem, Gilles Lecarpentier, Edouard Luton, Dominique Perrotin, Franck Rozenberg, Patrick Schmitz, Thomas Sroussi, Jeremy Vayssière, Christophe Verspyck, Eric Vivanti, Alexandre Winer, Norbert
Source	Elsevier; Medline; PMC
abstract	OBJECTIVE: To describe the course over time of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in French women from the beginning of the pandemic until mid-April, the risk profile of women with respiratory complications, and short-term pregnancy outcomes. METHODS: We collected a case series of pregnant women with COVID-19 in a research network of 33 French maternity units between March 1 and April 14, 2020. All cases of SARS-CoV-2 infection confirmed by a positive result on real-time reverse transcriptase polymerase chain reaction tests of a nasal sample and/or diagnosed by a computed tomography chest scan were included and analyzed. The primary outcome measures were COVID-19 requiring oxygen (oxygen therapy or noninvasive ventilation) and critical COVID-19 (requiring invasive mechanical ventilation or extracorporeal membrane oxygenation, ECMO). Demographic data, baseline comorbidities, and pregnancy outcomes were also collected. RESULTS: Active cases of COVID-19 increased exponentially during March 1-31, 2020; the numbers fell during April 1-14, after lockdown was imposed on March 17. The shape of the curve of active critical COVID-19 mirrored that of all active cases. By April 14, among the 617 pregnant women with COVID-19, 93 women (15.1%; 95%CI 12.3-18.1) had required oxygen therapy and 35 others (5.7%; 95%CI 4.0-7.8) had had a critical form of COVID-19. The severity of the disease was associated with age older than 35 years and obesity, as well as preexisting diabetes, previous preeclampsia, and gestational hypertension or preeclampsia. One woman with critical COVID-19 died (0.2%; 95%CI 0-0.9). Among the women who gave birth, rates of preterm birth in women with non-severe, oxygen-requiring, and critical COVID-19 were 13/123 (10.6%), 14/29 (48.3%), and 23/29 (79.3%) before 37 weeks and 3/123 (2.4%), 4/29 (13.8%), and 14/29 (48.3%) before 32 weeks, respectively. One neonate in the critical group died from prematurity. CONCLUSION: COVID-19 can be responsible for significant rates of severe acute, potentially deadly, respiratory distress syndromes. The most vulnerable pregnant women, those with comorbidities, may benefit particularly from prevention measures such as a lockdown.
has issue date	2020-06-04(xsd:dateTime)
bibo:doi	10.1016/j.jogoh.2020.101826
bibo:pmid	32505805
has license	no-cc
sha1sum (hex)	2f50996dbe46068e4a5ac9d7bb4b4c8e781ffc0d
schema:url	https://doi.org/10.1016/j.jogoh.2020.101826
resource representing a document's title	A snapshot of the Covid-19 pandemic among pregnant women in France
has PubMed Central identifier	PMC7270811
has PubMed identifier	32505805
schema:publication	J Gynecol Obstet Hum Reprod
resource representing a document's body	covid:2f50996dbe46068e4a5ac9d7bb4b4c8e781ffc0d#body_text
is schema:about of	named entity 'profile' named entity 'WOMEN' named entity 'risk' named entity 'time' named entity 'infection' named entity 'pregnancy' named entity 'severe acute respiratory syndrome coronavirus 2' named entity 'infection' named entity 'Covid' named entity 'severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)' named entity 'confidence intervals' named entity 'ECMO' named entity 'respiratory disease' named entity 'pregnant women' named entity 'research hospital' named entity 'pregnant women' named entity 'Stata' named entity 'preeclampsia' named entity 'pregnant women' named entity 'comorbidities' named entity 'pregnant women' named entity 'COVID' named entity 'medical history' named entity 'SARS-CoV-2' named entity 'chest scan' named entity 'COVID-19' named entity 'angiotensin-converting enzyme 2' named entity 'neonatal intensive care unit' named entity 'gestational hypertension' named entity 'pregnant women' named entity 'Shortness of breath' named entity 'COVID' named entity 'COVID' named entity 'neonatal' named entity 'higher risk' named entity 'general Chinese' named entity 'respiratory complications' named entity 'preeclampsia' named entity 'infection' named entity 'fetal' named entity 'active COVID-19 cases' named entity 'respiratory support' named entity 'preterm births' named entity 'obesity' named entity 'COVID-19' named entity 'COVID-19' named entity 'Smoking during pregnancy' named entity 'College Station, Texas' named entity 'follow-up'

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