About: Acute disseminated encephalomyelitis progressing to multiple sclerosis: Are infectious triggers involved?

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About: Acute disseminated encephalomyelitis progressing to multiple sclerosis: Are infectious triggers involved? Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Acute disseminated encephalomyelitis progressing to multiple sclerosis: Are infectious triggers involved?
Creator	Alexander, Anaïs Smyk, Daniel Walker, Martin Walker, Mary
Source	Medline; PMC
abstract	Acute disseminated encephalomyelitis (ADEM) and multiple sclerosis (MS) are demyelinating disorders affecting the central nervous system. An autoimmune aetiology has been proposed for both. ADEM principally affects adolescents following acute infection by a variety of pathogens and has also been reported to occur following vaccination. ADEM typically resolves following medical treatment, whereas MS follows a more relapsing and remitting course. The pathogenesis of MS remains unclear, but it is thought that a combination of infectious and non-infectious environmental factors and host genetics act synergistically to cause disease. A variety of viruses, including Epstein Barr virus, cytomegalovirus, herpes simplex virus and varicella zoster virus, have been implicated as possible infectious triggers. The similar clinical and pathological presentation of ADEM and MS presents a diagnostic challenge for distinguishing ADEM from a first episode of MS. Some cases of ADEM progress to MS for reasons that are not currently clear. This review examines the evidence for infectious agents as triggers for ADEM progressing to MS and suggests potential methods that may facilitate identification of infectious agents that may be responsible for the pathogenesis of ADEM to MS.
has issue date	2014-03-26(xsd:dateTime)
bibo:doi	10.1007/s12026-014-8499-y
bibo:pmid	24668297
has license	no-cc
sha1sum (hex)	31285ce7295f8bdd4cd615d16ca75356d61c98d9
schema:url	https://doi.org/10.1007/s12026-014-8499-y
resource representing a document's title	Acute disseminated encephalomyelitis progressing to multiple sclerosis: Are infectious triggers involved?
has PubMed Central identifier	PMC7091333
has PubMed identifier	24668297
schema:publication	Immunol Res
resource representing a document's body	covid:31285ce7295f8bdd4cd615d16ca75356d61c98d9#body_text
is schema:about of	named entity 'ADEM' named entity 'presentation' named entity 'evidence' named entity 'presents' named entity 'THOUGHT' named entity 'PROGRESSING TO' named entity 'DIAGNOSTIC' named entity 'HOST' named entity 'ACUTE INFECTION' named entity 'NON-' named entity 'VIRUSES' named entity 'CHALLENGE' named entity 'ADOLESCENTS' named entity 'ACUTE DISSEMINATED ENCEPHALOMYELITIS' named entity 'PATHOGENS' named entity 'DISTINGUISHING' named entity 'EVIDENCE FOR' named entity 'VACCINATION' named entity 'METHODS' named entity 'POTENTIAL' named entity 'RESPONSIBLE' named entity 'FOLLOWING' named entity 'VARIETY' named entity 'PROPOSED' named entity 'ADEM' named entity 'POSSIBLE' named entity 'TO CAUSE DISEASE' named entity 'INFECTIOUS' named entity 'HAVE' named entity 'ACT' named entity 'REPORTED' named entity 'PROGRESS' named entity 'EPISODE OF' named entity 'HERPES SIMPLEX VIRUS' named entity 'REASONS' named entity 'PRESENTATION' named entity 'REMITTING' named entity 'PROGRESSING TO' named entity 'INFECTIOUS AGENTS' named entity 'FIRST EPISODE' named entity 'IDENTIFICATION' named entity 'CENTRAL NERVOUS SYSTEM' named entity 'SIMILAR' named entity 'TRIGGERS' named entity 'EPSTEIN BARR VIRUS' named entity 'AUTOIMMUNE' named entity 'MEDICAL TREATMENT' covid:arg/31285ce7295f8bdd4cd615d16ca75356d61c98d9 named entity 'VARICELLA ZOSTER VIRUS' named entity 'FOLLOWS' named entity 'CURRENTLY' named entity 'REVIEW' named entity 'INFECTIOUS' named entity 'ACUTE DISSEMINATED ENCEPHALOMYELITIS' named entity 'INVOLVED' named entity 'MULTIPLE SCLEROSIS' named entity 'UNCLEAR' named entity 'AFFECTING' named entity 'CYTOMEGALOVIRUS' named entity 'ENVIRONMENTAL FACTORS' named entity 'MULTIPLE SCLEROSIS' named entity 'PRESENTS' named entity 'AETIOLOGY' named entity 'DEMYELINATING DISORDERS' named entity 'BUT' named entity 'RELAPSING' named entity 'CLEAR' named entity 'COURSE' named entity 'OCCUR' named entity 'CLINICAL' named entity 'PATHOGENESIS' named entity 'CASES' named entity 'PATHOLOGICAL' named entity 'MS.' named entity 'TRIGGERS' named entity 'GENETICS' named entity 'INCLUDING' named entity 'COMBINATION'

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