About: Factors associated with recovery delay in a sample of patients diagnosed by MERS‐CoV rRT‐PCR: A Saudi Arabian multicenter retrospective study

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About: Factors associated with recovery delay in a sample of patients diagnosed by MERS‐CoV rRT‐PCR: A Saudi Arabian multicenter retrospective study Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Factors associated with recovery delay in a sample of patients diagnosed by MERS‐CoV rRT‐PCR: A Saudi Arabian multicenter retrospective study
Creator	Al-Jahdali, Hamdan Alsaab, Hanan Ahmed, Anwar Al Otaibi, Hazza Ali, Yosra Alghamdi, Mohammed Sakr, Ezzeldin Subedar, Alaa Alandonisi, M Alaqeel, \| Aloudah, M Alyahya, A Hamed, \| Johani, Al Munzir, \| Nouf, \| Salim Baharoon, \| Salma, \| Sameera, \| Siddiq, S
Source	Medline; PMC
abstract	BACKGROUND: Research evidence exists that poor prognosis is common in Middle East respiratory syndrome coronavirus (MERS‐CoV) patients. OBJECTIVES: This study estimates recovery delay intervals and identifies associated factors in a sample of Saudi Arabian patients admitted for suspected MERS‐CoV and diagnosed by rRT‐PCR assay. METHODS: A multicenter retrospective study was conducted on 829 patients admitted between September 2012 and June 2016 and diagnosed by rRT‐PCR procedures to have MERS‐CoV and non‐MERS‐CoV infection in which 396 achieved recovery. Detailed medical charts were reviewed for each patient who achieved recovery. Time intervals in days were calculated from presentation to the initial rRT‐PCR diagnosis (diagnosis delay) and from the initial rRT‐PCR diagnosis to recovery (recovery delay). RESULTS: The median recovery delay in our sample was 5 days. According to the multivariate negative binomial model, elderly (age ≥ 65), MERS‐CoV infection, ICU admission, and abnormal radiology findings were associated with longer recovery delay (adjusted relative risk (aRR): 1.741, 2.138, 2.048, and 1.473, respectively). Camel contact and the presence of respiratory symptoms at presentation were associated with a shorter recovery delay (expedited recovery) (aRR: 0.267 and 0.537, respectively). Diagnosis delay is a positive predictor for recovery delay (r = .421; P = .001). CONCLUSIONS: The study evidence supports that longer recovery delay was seen in patients of older age, MERS‐CoV infection, ICU admission, and abnormal radiology findings. Shorter recovery delay was found in patients who had camel contact and respiratory symptoms at presentation. These findings may help us understand clinical decision making on directing hospital resources toward prompt screening, monitoring, and implementing clinical recovery and treatment strategies.
has issue date	2018-04-25(xsd:dateTime)
bibo:doi	10.1111/irv.12560
bibo:pmid	29624866
has license	cc-by
sha1sum (hex)	32ffbe671caf791831bb7516b550b4b27240a5f0
schema:url	https://doi.org/10.1111/irv.12560
resource representing a document's title	Factors associated with recovery delay in a sample of patients diagnosed by MERS‐CoV rRT‐PCR: A Saudi Arabian multicenter retrospective study
has PubMed Central identifier	PMC6086845
has PubMed identifier	29624866
schema:publication	Influenza Other Respir Viruses
resource representing a document's body	covid:32ffbe671caf791831bb7516b550b4b27240a5f0#body_text
is schema:about of	named entity 'Saudi' named entity 'MERS-CoV' named entity 'MERS-CoV' named entity 'retrospective study' named entity 'ARABIAN' named entity 'PATIENTS' named entity 'STUDY' named entity 'COMMON' named entity 'INFECTION' named entity '396' named entity 'RECOVERY' named entity 'BACKGROUND' named entity 'NON-' named entity 'RESEARCH' named entity 'SUSPECTED' named entity 'ASSOCIATED' named entity 'METHODS' named entity 'DIAGNOSED' named entity 'RETROSPECTIVE STUDY' named entity 'DELAY' named entity 'SAUDI' named entity 'MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS' named entity 'HAVE' named entity 'ASSOCIATED WITH' named entity 'RRT-PCR' named entity 'SAMPLE' named entity 'RECOVERY' named entity 'DELAY' named entity 'ESTIMATES' named entity 'ADMITTED' named entity 'SEPTEMBER' named entity 'SAMPLE' named entity 'POOR PROGNOSIS' named entity 'MERS-COV' named entity 'PROCEDURES' named entity 'EVIDENCE' named entity 'SAUDI' named entity 'PATIENTS' named entity 'RRT-PCR' named entity 'OBJECTIVES' named entity 'DIAGNOSED' named entity 'RETROSPECTIVE STUDY' named entity 'INTERVALS' named entity 'JUNE' named entity 'PCR ASSAY' named entity 'ARABIAN' covid:arg/32ffbe671caf791831bb7516b550b4b27240a5f0 named entity 'June' named entity 'Objectives' named entity 'assay' named entity 'prognosis' named entity 'MERS-CoV' named entity 'MERS-CoV' named entity 'exists' named entity 'sample' named entity 'medical records' named entity 'ICU' named entity 'study population' named entity 'symptom' named entity 'PCR diagnosis' named entity 'mortality rate' named entity 'MERS-CoV'

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