About: Closed-type pre-treatment device for point-of-care testing of sputum

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Closed-type pre-treatment device for point-of-care testing of sputum
Creator	Lee, Kyu-Sung Lee, Min-Young Park, Hyun-Ju Woo, Ayoung Cha, Jae
Source	Medline; PMC
abstract	The procedures and protocols for the pre-treatment of sputum specimens, mainly used for the diagnosis of pneumonia, are complex, labor intensive, and require skilled specialists working in a biosafety containment laboratory because of sample infectivity. In this study, we developed the first portable, low-power pre-treatment device that carries out all sputum pre-treatment procedures (liquefaction, homogenization, dissolution, and inactivation) in an enclosed space. Designed to simultaneously employ chemical and mechanical dissolution in the enclosed chamber, this device eliminates the risk of transmission and improves the effectiveness of sputum dissolution and pathogen detection. This device is expected to allow for the pre-treatment of infectious sputum specimens outside of a biosafety containment laboratory. Used in conjunction with automated genome extraction and detection systems, this device should make the on-site diagnosis using infectious sputum specimens possible.
has issue date	2018-11-07(xsd:dateTime)
bibo:doi	10.1038/s41598-018-34781-1
bibo:pmid	30405199
has license	cc-by
sha1sum (hex)	3422bab59932dcb046a0dfe931eb71173130979f
schema:url	https://doi.org/10.1038/s41598-018-34781-1
resource representing a document's title	Closed-type pre-treatment device for point-of-care testing of sputum
has PubMed Central identifier	PMC6220321
has PubMed identifier	30405199
schema:publication	Sci Rep
resource representing a document's body	covid:3422bab59932dcb046a0dfe931eb71173130979f#body_text
is schema:about of	named entity 'DEVICE' named entity 'CLOSED' named entity 'The' named entity 'laboratory' named entity 'OPEN' named entity 'RISK OF' named entity 'DEVICE' named entity 'PROTOCOLS' named entity 'STUDY' named entity 'AUTOMATED' named entity 'TRANSMISSION' named entity 'EMPLOY' named entity 'COMPLEX' named entity 'MECHANICAL' named entity 'CARRIES' named entity 'SKILLED' named entity 'INFECTIOUS' named entity 'EFFECTIVENESS' named entity 'DETECTION' named entity 'INACTIVATION' named entity 'USED' named entity 'LABORATORY' named entity 'LABOR' named entity 'BIOSAFETY' named entity 'SYSTEMS' named entity 'PROCEDURES' named entity 'POSSIBLE' named entity 'LOW' named entity 'USING' named entity 'EXPECTED' named entity 'CONJUNCTION' named entity 'ENCLOSED' named entity 'CONTAINMENT' named entity 'SPECIMENS' named entity 'HOMOGENIZATION' named entity 'INFECTIVITY' named entity 'POINT-OF-CARE TESTING' named entity 'SPUTUM' named entity 'TYPE' named entity 'OPEN' named entity 'EXTRACTION' named entity 'MAKE' named entity 'PORTABLE' named entity 'SIMULTANEOUSLY' named entity 'WORKING' named entity 'POWER' named entity 'SPUTUM' named entity 'CHEMICAL' named entity 'SPECIALISTS' named entity 'OUTSIDE' named entity 'SITE' named entity 'GENOME' named entity 'CHAMBER' named entity 'PATHOGEN DETECTION' named entity 'SAMPLE' named entity 'ALLOW' named entity 'SPACE' named entity 'DISSOLUTION' named entity 'IMPROVES' covid:arg/3422bab59932dcb046a0dfe931eb71173130979f named entity 'intensive' named entity 'chamber' named entity 'device' named entity 'device' named entity 'sputum' named entity 'chemical reagents' named entity 'dissolution' named entity 'procedures' named entity 'sputum' named entity 'genome' named entity 'biosafety' named entity 'low-power' named entity 'sputum' named entity 'pathogen' named entity 'sputum' named entity 'carries' named entity 'absorbance'

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